2,4-Bis(4-hydroxybenzyl)phenol

Base Information

• Chemical Name: 2,4-Bis(4-hydroxybenzyl)phenol
• CAS No.: 34826-64-7
• Molecular Formula: C20H18 O3
• Molecular Weight: 306.361
• Hs Code.: 2907299090
• UNII: JZ8542V589
• DSSTox Substance ID: DTXSID70188364
• Nikkaji Number: J562.614E
• Wikipedia: 2,4-Bis(4-hydroxybenzyl)phenol
• Wikidata: Q4596774
• ChEMBL ID: CHEMBL3286745
• Mol file: 34826-64-7.mol

Synonyms:2,4-bis(4-hydroxybenzyl)phenol;Bis(HOBz)phenol

Chemical Property of 2,4-Bis(4-hydroxybenzyl)phenol

Chemical Property:

• Vapor Pressure: 2.62E-12mmHg at 25°C
• Melting Point: 142-145 °C(Solv: acetic acid, 35% (64-19-7); water (7732-18-5))
• Boiling Point: 540.8°Cat760mmHg
• PKA: 10.20±0.10(Predicted)
• Flash Point: 255.6°C
• PSA: 60.69000
• Density: 1.258g/cm³
• LogP: 3.98500
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 306.125594432
• Heavy Atom Count: 23
• Complexity: 343

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC2=CC(=C(C=C2)O)CC3=CC=C(C=C3)O)O
• Use Description: 2,4-bis(4-hydroxybenzyl)phenol is a chemical compound with a range of potential applications across various fields. In the pharmaceutical and medical industry, it is of interest due to its antioxidant properties and potential health benefits. It may be studied for its role in combating oxidative stress and inflammation, making it a candidate for research related to aging, neurodegenerative diseases, and chronic health conditions. In the field of materials science, this compound can be used as a building block for the synthesis of specialized polymers, resins, or materials with enhanced thermal stability and resistance to UV radiation. Additionally, in academic research, it serves as a reference compound for studying antioxidant mechanisms and the development of novel materials or drug candidates. Its versatility as an antioxidant and chemical building block underscores its significance in pharmaceuticals, materials science, and scientific research, offering potential insights into health and material-related applications while contributing to progress in these diverse fields.

Technology Process of 2,4-Bis(4-hydroxybenzyl)phenol

There total 9 articles about 2,4-Bis(4-hydroxybenzyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-monochlorophenol (95-57-8) → 2,4-bis(4-hydroxybenzyl)phenol (34826-64-7)

Guidance literature:

Multi-step reaction with 3 steps

2: H₂SO₄

3: nickel-aluminium-alloy; aqueous NaOH

With sodium hydroxide; aluminum nickel; sulfuric acid;

Reference yield:

2,6-dibromo-4-bromomethyl-phenol (5532-75-2) → 2,4-bis(4-hydroxybenzyl)phenol (34826-64-7)

Guidance literature:

Multi-step reaction with 3 steps

2: H₂SO₄

3: nickel-aluminium-alloy; aqueous NaOH

With sodium hydroxide; aluminum nickel; sulfuric acid;

Reference yield:

2,6-dibromo-2'-chloro-4,4'-methanediyl-di-phenol (875227-87-5) → 2,4-bis(4-hydroxybenzyl)phenol (34826-64-7)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄

2: nickel-aluminium-alloy; aqueous NaOH

With sodium hydroxide; aluminum nickel; sulfuric acid;

upstream raw materials:

(4-hydroxyphenyl)methanol

bis-(4-hydroxyphenyl)methane

2-chloro-4,6-bis-(3,5-dibromo-4-hydroxy-benzyl)-phenol

2-monochlorophenol