2,4-Dichlorobenzaldehyde oxime

Base Information

• Chemical Name: 2,4-Dichlorobenzaldehyde oxime
• CAS No.: 56843-28-8
• Molecular Formula: C7H5 Cl2 N O
• Molecular Weight: 190.029
• Hs Code.: 2913000090
• European Community (EC) Number: 640-873-0
• NSC Number: 75589,47499
• Wikidata: Q76306195
• Mol file: 56843-28-8.mol

Synonyms:2,4-Dichlorobenzaldehyde oxime;56843-28-8;2,4-Dichlorobenzaldoxime;(E)-2,4-dichlorobenzaldehyde oxime;N-[(2,4-dichlorophenyl)methylidene]hydroxylamine;Benzaldoxime,4-dichloro-;WLN: QNU1R BG DG;2,4-Dichorobenzaldehyde oxime;Benzaldehyde,4-dichloro-, oxime;(NE)-N-[(2,4-dichlorophenyl)methylidene]hydroxylamine;HMS566E19;NSC47499;NSC75589;MFCD00173694;NSC-47499;NSC-75589;AKOS000304448;NCGC00323560-01;CS-0235447;CS-0356734;EN300-15685;AB01319032-02;Z49568347

Chemical Property of 2,4-Dichlorobenzaldehyde oxime

Chemical Property:

• Vapor Pressure: 0.00319mmHg at 25°C
• Melting Point: 134℃
• Boiling Point: 271.3°Cat760mmHg
• Flash Point: 117.9°C
• PSA: 32.59000
• Density: 1.38g/cm³
• LogP: 2.80150
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 188.9748192
• Heavy Atom Count: 11
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

2,4-dichlorobenzaldehydeoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Cl)C=NO
• Isomeric SMILES: C1=CC(=C(C=C1Cl)Cl)/C=N/O

Technology Process of 2,4-Dichlorobenzaldehyde oxime

There total 7 articles about 2,4-Dichlorobenzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,4-dichlorobenzaldeyhde (874-42-0) → 2,4-dichlorobenzaldoxime (56843-28-8)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 20 ℃; for 2h; Cooling with ice;

Reference yield: 96.0%

2-((2,4-dichlorobenzyl)oxy)tetrahydro-2H-pyran (391200-38-7) → 2,4-dichlorobenzaldoxime (56843-28-8)

Guidance literature:

With trichloroisocyanuric acid; hydroxylamine hydrochloride; In neat (no solvent); at 110 ℃; for 0.666667h; Green chemistry;

DOI:10.1080/10426507.2014.990015

Reference yield: 90.0%

2,4-dichlorobenzyl trimethysilyl ether (624286-51-7) → 2,4-dichlorobenzaldoxime (56843-28-8)

Guidance literature:

With trichloroisocyanuric acid; hydroxylamine hydrochloride; In neat (no solvent); at 100 ℃; for 2h; Green chemistry;

DOI:10.1080/10426507.2014.990015

upstream raw materials:

2,4-dichlorobenzaldeyhde

N'-(2,4-dichlorobenzylidene)-2-iminochromen-3-carbohydrazide

2,4-dichloro-benzenemethanamine

2,4-dichlorotoluene

Downstream raw materials:

2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride

4-[1-(2,4-Dichloro-phenyl)-meth-(Z)-ylideneaminooxy]-3-nitro-benzoic acid methyl ester

2,4-dichlorobenzylnitrile

2,4-Dichloro-benzaldehyde O-(2,4-dinitro-phenyl)-oxime

Refernces

• 1、 -. "Microwave synthesis method of benzaldoxime compounds". Paragraph 0076-0079. . Retrieved 2020/12/08.
• 2、 Liu, Zhiyan,Cao, Jiangping,Yan, Xiaoting,Cheng, Wanqing,Wang, Xiaoguang,Yang, Ruige,Guo, Yong. "Discovery of Natural Product-Based Fungicides (II): Semisynthesis and Biological Activity of Sarisan Attached 3-Phenylisoxazolines as Antifungal Agents". . . Retrieved 2020/12/09.