7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Base Information Edit

Chemical Name:7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.:80370-57-6
Molecular Formula:C19H17N5O7S3
Molecular Weight:523.571
Hs Code.:DERIVATION
European Community (EC) Number:688-302-4
DSSTox Substance ID:DTXSID70861024
NCI Thesaurus Code:C81036
RXCUI:1311521
Wikipedia:Ceftiofur
Mol file:80370-57-6.mol

7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Synonyms:ceftiofur;ceftiofur hydrochloride;ceftiofur sodium;Naxcel;U 64279A;U-64279E

Suppliers and Price of 7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ceftiofur
500ul
$ 360.00

Usbiological
Ceftiofur
500ul
$ 355.00

Sigma-Aldrich
Ceftiofur VETRANAL?, analytical standard
100 mg
$ 95.00

Sigma-Aldrich
Ceftiofur VETRANAL
100mg-r
$ 92.10

AvaChem
Ceftiofur
1g
$ 239.00

American Custom Chemicals Corporation
CEFTIOFUR 95.00%
1G
$ 1686.30

American Custom Chemicals Corporation
CEFTIOFUR 95.00%
100MG
$ 716.10

AccelPharmtech
Ceftiofur 99%
500G
$ 540.00

AccelPharmtech
Ceftiofur 99%
200G
$ 320.00

Total 120 raw suppliers

Chemical Property of 7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Edit

Chemical Property:

Appearance/Colour:White to off-white powder
Refractive Index:1.819
PKA:2.62±0.50(Predicted)
PSA：256.26000
Density:1.81 g/cm³
LogP:1.89100
Storage Temp.:0-6°C
Solubility.:DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated)
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:9
Exact Mass:523.02901142
Heavy Atom Count:34
Complexity:945

Purity/Quality:

99% ^*data from raw suppliers

Ceftiofur ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)O
Uses Animal-specific antibiotic medicines used for treating Gram-positive and Gram-negative bacteria and Mycoplasma infection. Veterinary (original powder) antifungal A third generation cephalosporin antibiotic for used in veterinary medicine. It is resistant to antibiotic resistance enzyme beta-lactamase.

Technology Process of 7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

There total 8 articles about 7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

: 80370-59-8
(6R,7R)-7-amino-3-(furan-2-carbonylsulfanylmethyl)cephalosporanic acid

: AE-active ester

: 80370-57-6
ceftiofur

Guidance literature:: (6R,7R)-7-amino-3-(furan-2-carbonylsulfanylmethyl)cephalosporanic acid; With triethylamine; In dichloromethane; at -5 - 0 ℃; for 1h; Large scale;

AE-active ester; In dichloromethane; water; at 5 - 7 ℃; for 3.5h; Large scale;