2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethylethanaminium chloride

Base Information

• Chemical Name: 2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethylethanaminium chloride
• CAS No.: 63918-01-4
• Molecular Formula: C₁₄H₂₂ClNO*ClH
• Molecular Weight: 292.249
• Mol file: 63918-01-4.mol

Synonyms:Ethanamine,2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethyl-, hydrochloride (9CI)

Chemical Property of 2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethylethanaminium chloride

Chemical Property:

• Vapor Pressure: 0.000163mmHg at 25°C
• Boiling Point: 330.7°C at 760 mmHg
• Flash Point: 153.8°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethylethanaminium chloride

There total 3 articles about 2-chloro-N-[2-(3,4-dimethylphenoxy)ethyl]-N-ethylethanaminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-{ethyl-[2-(3,4-dimethyl-phenoxy)-ethyl]-amino}-ethanol (858257-45-1) → ethyl-(2-chloro-ethyl)-[2-(3,4-dimethyl-phenoxy)-ethyl]-amine; hydrochloride (63918-01-4)

Guidance literature:

With thionyl chloride; chloroform;

DOI:10.1021/ja01165a004

Reference yield:

2-(3,4-dimethyl-phenoxy)-ethanol (34221-43-7) → ethyl-(2-chloro-ethyl)-[2-(3,4-dimethyl-phenoxy)-ethyl]-amine; hydrochloride (63918-01-4)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂; pyridine; CHCl₃

2: 170 °C

3: SOCl₂; CHCl₃

With pyridine; thionyl chloride; chloroform;

DOI:10.1021/ja01165a004

Reference yield:

(2-chloro-ethyl)-(3,4-dimethyl-phenyl)-ether (79096-58-5) → ethyl-(2-chloro-ethyl)-[2-(3,4-dimethyl-phenoxy)-ethyl]-amine; hydrochloride (63918-01-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 170 °C

2: SOCl₂; CHCl₃

With thionyl chloride; chloroform;

DOI:10.1021/ja01165a004

upstream raw materials:

2-{ethyl-[2-(3,4-dimethyl-phenoxy)-ethyl]-amino}-ethanol

2-(3,4-dimethyl-phenoxy)-ethanol

(2-chloro-ethyl)-(3,4-dimethyl-phenyl)-ether