3-Amidinopyridinium chloride

Base Information

• Chemical Name: 3-Amidinopyridinium chloride
• CAS No.: 7356-60-7
• Molecular Formula: C₆H₇N₃*ClH
• Molecular Weight: 157.603
• Hs Code.: 29333990
• Mol file: 7356-60-7.mol

Synonyms:3-AMIDINOPYRIDINIUM CHLORIDE;AMY32831;BP-11319;J-523606

Chemical Property of 3-Amidinopyridinium chloride

Chemical Property:

• Vapor Pressure: 0.0374mmHg at 25°C
• Melting Point: 188 °C
• Boiling Point: 240.7 °C at 760 mmHg
• Flash Point: 99.4 °C
• PSA: 71.99000
• LogP: 1.90340
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 157.0406750
• Heavy Atom Count: 10
• Complexity: 105

Purity/Quality:

98% ^*data from raw suppliers

Nicotinimidamide Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi，Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22-22
• Safety Statements: 26-36/37/39-22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN=C1)C(=[NH2+])N.[Cl-]
• Uses: Nicotinimidamide Hydrochloride is a useful synthetic compound.

Technology Process of 3-Amidinopyridinium chloride

There total 3 articles about 3-Amidinopyridinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ pyridine-3-carboxamidine hydrochloride (7356-60-7,63265-42-9)

Guidance literature:

Reference yield: 74.0%

pyridine-3-carbonitrile (100-54-9,121697-66-3,1232169-17-3,68271-95-4) → pyridine-3-carboxamidine hydrochloride (7356-60-7,63265-42-9)

Guidance literature:

pyridine-3-carbonitrile; With sodium methylate; In methanol; at 20 ℃;

With ammonium chloride; In methanol; for 4h; Reflux;

Reference yield:

methyl pyridine-3-carboximidate (57869-84-8) → pyridine-3-carboxamidine hydrochloride (7356-60-7,63265-42-9)

Guidance literature:

With ammonium chloride; In methanol; for 4h; Heating;

DOI:10.1021/jm00166a023

upstream raw materials:

methyl pyridine-3-carboximidate

pyridine-3-carbonitrile

Downstream raw materials:

4-methyl-2-(pyridin-3-yl)-1H-imidazole-5-carboxylic acid

4-amino-2-(3-pyridinyl)pyrimidine

4-chloro-6-methyl-2-(pyridin-3'-yl)pyrimidine

2-pyridin-3-yl-pyrimidine-4,6-diol

Refernces

• 1、 -. "AMINOPYRIMIDINE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS". Paragraph 636-642. . Retrieved 2021/10/02.
• 2、 Ko?í?ek, Milan,?těpánek, Ond?ej,Parkan, Kamil,Berenguer Albi?ana, Carlos,Pávová, Marcela,Weber, Jan,Kr?usslich, Hans-Georg,Konvalinka, Jan,Machara, Ale?. "Synthesis and evaluation of 2-pyridinylpyrimidines as inhibitors of HIV-1 structural protein assembly". supporting information. p. 3487 - 3490. Retrieved 2016/07/21.