3-(4-oxo-4H-pyridin-1-yl)-propionitrile

Base Information

• Chemical Name: 3-(4-oxo-4H-pyridin-1-yl)-propionitrile
• CAS No.: 68634-53-7
• Molecular Formula: C₈H₈N₂O
• Molecular Weight: 148.164
• Mol file: 68634-53-7.mol

Synonyms:3-(4-oxo-4H-pyridin-1-yl)-propionitrile

Chemical Property of 3-(4-oxo-4H-pyridin-1-yl)-propionitrile

Chemical Property:

• Melting Point: 109-110 °C
• Boiling Point: 310.2±42.0 °C(Predicted)
• Density: 1.156±0.06 g/cm3(Predicted)

Purity/Quality:

95% ^*data from raw suppliers

3-(4-Oxopyridin-1(4H)-yl)propanenitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-oxo-4H-pyridin-1-yl)-propionitrile

There total 3 articles about 3-(4-oxo-4H-pyridin-1-yl)-propionitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridin-4-ol (626-64-2,157061-69-3) + acrylonitrile (107-13-1,25014-41-9) → 3-(4-oxo-4H-pyridin-1-yl)-propionitrile (68634-53-7)

Guidance literature:

With 4-hydroxypyridine sodium salt;

DOI:10.1021/ja01170a092

Reference yield:

4-pyridone (108-96-3,26266-70-6) + acrylonitrile (107-13-1,25014-41-9) → 3-(4-oxo-4H-pyridin-1-yl)-propionitrile (68634-53-7)

Guidance literature:

With potassium chloride; hydroxide; In water; at 25 ℃; Rate constant; Equilibrium constant;

DOI:10.1021/ja00180a034

Reference yield:

→ 3-(4-oxo-4H-pyridin-1-yl)-propionitrile (68634-53-7)

Guidance literature:

4-Pyridon, Acrylnitril/Methanol, Rueckfluss;

upstream raw materials:

pyridin-4-ol

acrylonitrile

4-pyridone

Downstream raw materials:

4-pyridone

acrylonitrile

Refernces