Technology Process of (3R,4R)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman
There total 30 articles about (3R,4R)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
water; acetone; tert-butyl alcohol;
at 0 ℃;
for 3h;
DOI:10.1039/c5ob00216h
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 2.86 g / HCl / ethanol / 25 h / Ambient temperature
2: 867 mg / anhydr. K2CO3 / dimethylformamide / 2 h / 100 °C
3: 516 mg / hydrogen peroxide, aq. NaOH / acetone; methanol / 24 h / Ambient temperature
4: LiAlH4 / tetrahydrofuran / 1.) 0 deg C; room temp., 2 h
5: 28 mg / hydrogen / Pd-C (5percent) / acetone; methanol / 2 h
6: 5 mg / anhydr. K2CO3 / acetone / 3 h / Heating
With
hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; hydrogen; dihydrogen peroxide; potassium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1248/cpb.35.2761
