Ufenamate

Base Information

• Chemical Name: Ufenamate
• CAS No.: 67330-25-0
• Molecular Formula: C18H18 F3 N O2
• Molecular Weight: 337.342
• European Community (EC) Number: 614-050-1
• UNII: 8Z7O7C1SLZ
• DSSTox Substance ID: DTXSID30867269
• Nikkaji Number: J22.205D
• Wikipedia: Ufenamate
• Wikidata: Q7877498
• NCI Thesaurus Code: C152791
• ChEMBL ID: CHEMBL2105605
• Mol file: 67330-25-0.mol

Synonyms:butyl flufenamate;ufenamate

Chemical Property of Ufenamate

Chemical Property:

• Vapor Pressure: 2.01E-06mmHg at 25°C
• Refractive Index: 1.5530 to 1.5570
• Boiling Point: 394.3oC at 760 mmHg
• PKA: -2.36±0.50(Predicted)
• Flash Point: 192.2oC
• PSA: 38.33000
• Density: 1.22g/cm3
• LogP: 5.47890
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 6.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 337.12896330
• Heavy Atom Count: 24
• Complexity: 400

Purity/Quality:

99% ^*data from raw suppliers

Ufenamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F
• Description: Butyl flufenamate is a topical, non-steroidal antiinflammatory agent indicated for the treatment of acute and chronic eczema; contact, seborrheic, and atopic dermatitis; and herpes zoster.
• Uses: Ufenamate serves an ointment in treatment of facial hormone-dependent dermatitis, treatment of cephalic chronic eczema and neurodermatitis

Technology Process of Ufenamate

There total 1 articles about Ufenamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ n-Butyl N-(3-trifluoromethylphenyl)anthranilate (67330-25-0)

Guidance literature:

K-Salz d.entspr.Carbonsaeure, Butylbromid;

Reference yield: 30.0%

n-Butyl N-(3-trifluoromethylphenyl)anthranilate (67330-25-0) → 2-(2-(3-trifluoromethylphenylamino)-phenyl)-2-imidazoline (83265-70-7)

Guidance literature:

With ethylenediamine; In methanol;

Downstream raw materials:

2-(2-(3-trifluoromethylphenylamino)-phenyl)-2-imidazoline