potassium (1-phenylethyl)trifluoroborate

Base Information

• Chemical Name: potassium (1-phenylethyl)trifluoroborate
• CAS No.: 329976-80-9
• Molecular Formula: C₈H₉BF₃*K
• Molecular Weight: 212.064
• Mol file: 329976-80-9.mol

Synonyms:potassium (1-phenylethyl)trifluoroborate

Chemical Property of potassium (1-phenylethyl)trifluoroborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of potassium (1-phenylethyl)trifluoroborate

There total 3 articles about potassium (1-phenylethyl)trifluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → potassium (1-phenylethyl)trifluoroborate (329976-80-9)

Guidance literature:

styrene; With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 1,4-di(diphenylphosphino)-butane; benzo[1,3,2]dioxaborole; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

With 2,3-dimethyl-2,3-butane diol; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

With potassium hydrogen difluoride; In methanol; water;

DOI:10.1016/j.tet.2011.09.055

Reference yield:

→ potassium (1-phenylethyl)trifluoroborate (329976-80-9)

Guidance literature:

1-phenylethylmagnesium halide; With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃;

With potassium hydrogen bifluoride; water; In tetrahydrofuran; at 0 - 20 ℃; Further stages.;

DOI:10.1021/ol006896u

Reference yield:

potassium hydrogenfluoride (1279123-63-5) + (R)-4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane (257298-92-3) → potassium (1-phenylethyl)trifluoroborate (329976-80-9)

Guidance literature:

In methanol; react. of KHF2 and (CH3)(C6H5)CHB(OC(CH3)2)2; co-evapn. (MeOH/H2O); e.r. 97:3;

DOI:10.1002/anie.200901900

upstream raw materials:

potassium hydrogenfluoride

(R)-4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane

styrene

Downstream raw materials:

N-(1-phenylethyl)cinnamamide

N-(1-phenylethyl)dodecanamide

N-(1-phenylethyl)hex-5-ynamide

N-(1-phenylethyl)hex-5-enamide

Refernces

• 1、 Ros, Abel,Aggarwal, Varinder K.. "Complete stereoretention in the rhodium-catalyzed 1,2-addition of chiral secondary and tertiary alkyl potassium trifluoroborate salts to aldehydes". . p. 6289 - 6292. Retrieved 2009/12/06.