Technology Process of Cytidylyl-(3'-5')-cytidine
There total 16 articles about Cytidylyl-(3'-5')-cytidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: p-toluenesulfonic acid / CH2Cl2; methanol / 0.25 h / 0 °C
2: 1) ZnCl2 2) concentrated ammonia 3) 0.01N hydrochloric acid / 1) pyridine, water, 24h room temperature 2) 5h 50 deg C 3) 18h 20 deg C
With
hydrogenchloride; ammonia; toluene-4-sulfonic acid; zinc(II) chloride;
In
methanol; dichloromethane;
DOI:10.1021/jo01304a042
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 8-quinolinesulfonyl chloride / 1) pyridine, 6h room temperature 2) pyridine, 24h room temperature
2: p-toluenesulfonic acid / CH2Cl2; methanol / 0.25 h / 0 °C
3: 1) ZnCl2 2) concentrated ammonia 3) 0.01N hydrochloric acid / 1) pyridine, water, 24h room temperature 2) 5h 50 deg C 3) 18h 20 deg C
With
hydrogenchloride; quinoline-8-sulfonyl chloride; ammonia; toluene-4-sulfonic acid; zinc(II) chloride;
In
methanol; dichloromethane;
DOI:10.1021/jo01304a042
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 8-quinolinesulfonyl chloride / 1) pyridine, 6h room temperature 2) pyridine, 24h room temperature
2: p-toluenesulfonic acid / CH2Cl2; methanol / 0.25 h / 0 °C
3: 1) ZnCl2 2) concentrated ammonia 3) 0.01N hydrochloric acid / 1) pyridine, water, 24h room temperature 2) 5h 50 deg C 3) 18h 20 deg C
With
hydrogenchloride; quinoline-8-sulfonyl chloride; ammonia; toluene-4-sulfonic acid; zinc(II) chloride;
In
methanol; dichloromethane;
DOI:10.1021/jo01304a042