Norbornene oxide

Base Information

• Chemical Name: Norbornene oxide
• CAS No.: 3146-39-2
• Molecular Formula: C7H10 O
• Molecular Weight: 110.156
• Hs Code.: 2932999099
• Nikkaji Number: J83.677J
• Mol file: 3146-39-2.mol

Synonyms:norbornene oxide;844874-18-6;(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.02,4]octane;Rac-(1r,2s,4r,5s)-3-oxatricyclo[3.2.1.0,2,4]octane;SCHEMBL15423608;exo-2,3-Epoxynorbornane, 97%;CS-0260569;F83373;EN300-7543231;(1R,2S,4R,5S)-3-oxatricyclo[3.2.1.0,2,4]octane;Z1255379156;(1R,2S,4R,5S)-rel-3-Oxatricyclo[3.2.1.02,4]octane;(1S*,2R*,4S*,5R*)-3-Oxa-tricyclo[3.2.1.02,4]octane

Chemical Property of Norbornene oxide

Chemical Property:

• Vapor Pressure: 1.976mmHg at 25°C
• Melting Point: 122-124 °C(lit.)
• Refractive Index: 1.4409 (estimate)
• Boiling Point: 170.2°Cat760mmHg
• Flash Point: 10°C
• PSA: 12.53000
• Density: 1.159g/cm³
• LogP: 1.18370
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 110.073164938
• Heavy Atom Count: 8
• Complexity: 118

Purity/Quality:

98%,99%, ^*data from raw suppliers

exo-?2,?3-?Epoxynorbornane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-27-33-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2CC1C3C2O3
• Isomeric SMILES: C1C[C@H]2C[C@@H]1[C@H]3[C@@H]2O3
• Uses: exo-?2,?3-?Epoxynorbornane is a cytotoxic epoxide compound which also may act as a mutagen.

Technology Process of Norbornene oxide

There total 22 articles about Norbornene oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

norbornene (498-66-8) → exo-2,3-epoxynorbornane (278-74-0,3146-39-2,57378-36-6)

Guidance literature:

With tert.-butylhydroperoxide; In acetonitrile; at 80 ℃; for 24h; Reagent/catalyst; Solvent; Catalytic behavior;

DOI:10.1016/j.molcata.2014.12.004

Reference yield: 94.0%

norborn-2-ene (498-66-8) → exo-2,3-epoxynorbornane (278-74-0,3146-39-2,57378-36-6)

Guidance literature:

With tetra-n-butylammonium peroxomonosulfate; In water; at 70 ℃; for 0.75h;

DOI:10.1002/ejic.201200753

Reference yield: 21.0%

norborn-2-ene (498-66-8) → exo-2,3-epoxynorbornane (278-74-0,3146-39-2,57378-36-6) + exo-2,3-epoxynorbornane (844874-18-6)

Guidance literature:

With 1H-imidazole; dihydrogen peroxide; In water; acetonitrile; at 60 ℃; for 24h; under 760.051 Torr; regioselective reaction; Air;

DOI:10.1007/s00706-009-0215-6

upstream raw materials:

peracetic acid

norborn-2-ene

chloroform

sodium acetate

Downstream raw materials:

norborn-2-ene

C₁₈H₂₃NO₅

C₁₈H₂₁NO₅

C₉H₁₄O₃

Refernces

• 1、 Guo, Yingxiong,Xiao, Longqiang,Li, Pan,Zou, Wenhong,Zhang, Wenzhe,Hou, Linxi. "Binuclear molybdenum Schiff-base complex: An efficient catalyst for the epoxidation of alkenes". . . Retrieved 2019/07/10.
• 2、 Hou, Junying,Luan, Yi,Yu, Jie,Qi, Yue,Wang, Ge,Lu, Yunfeng. "Fabrication of hierarchical composite microspheres of copper-doped Fe3O4@P4VP@ZIF-8 and their application in aerobic oxidation". . p. 10127 - 10135. Retrieved 2016/12/07.