Etridiazole

Base Information

• Chemical Name: Etridiazole
• CAS No.: 2593-15-9
• Molecular Formula: C5H5 Cl3 N2 O S
• Molecular Weight: 247.532
• Hs Code.: 2934999024
• European Community (EC) Number: 219-991-8
• NSC Number: 524929
• UNII: 9F8237I875
• DSSTox Substance ID: DTXSID3032547
• Nikkaji Number: J3.391J
• Wikipedia: Etridiazole
• Wikidata: Q1371667
• ChEMBL ID: CHEMBL3183350
• Mol file: 2593-15-9.mol

Synonyms:ethazole;etridiazol;etridiazole;terrazole

Chemical Property of Etridiazole

Chemical Property:

• Vapor Pressure: 0.0273mmHg at 25°C
• Melting Point: 19.9°C
• Refractive Index: 1.5650 (estimate)
• Boiling Point: 254.7°Cat760mmHg
• PKA: 2.77 (very weak base)
• Flash Point: 107.8°C
• PSA: 63.25000
• Density: 1.574g/cm³
• LogP: 2.76350
• Storage Temp.: 0-6°C
• Solubility.: DMSO (Sparingly), Methanol (Slightly)
• Water Solubility.: 117 mg l-1(25 °C)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 245.918817
• Heavy Atom Count: 12
• Complexity: 154

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,N
• Statements: 21/22-23-40-50/53-20/21/22
• Safety Statements: 36/37-38-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Fungicides
• Canonical SMILES: CCOC1=NC(=NS1)C(Cl)(Cl)Cl
• Description: Etridiazole (20) was first described in 1969 and is a contact fungicide for control of soilborne diseases caused by Pythium and Phytophthora. Formulated as a WP (Terrazole), etridiazole may be used in a preventive program for control of Pythium blight in turf and of damping-off in ornamentals. It is also formulated in mixture with pentachloronitrobenzene (quintozene) as Terraclor Super X, which is applied in-furrow to cotton for control of seedling diseases (Rhizoctonia, Pythium, Fusarium). Application rates in cotton are equivalent to 1 to 1.5 and 0.26 to 0.39 kg ai ha?1 for PCNB and etridiazole, respectively.
• Uses: Etridiazole is a contact fungicide with protective and curative action that is used to control Phytophthora and Pythium spp. in ornamentals, cotton, peanuts, vegetables and turf. 5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole is a fungicide that can be incorporated into the soil or compost to control Phytophthora spp. and Pythium spp. Useful in cannabis testing kits as a component of pesticide mixes (P698235).

Technology Process of Etridiazole

There total 3 articles about Etridiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-bromotrichloroacetamidine + potassium ethyl xanthogenate (140-89-6) → 5-ethoxy-3-trichloromethyl-1,2,4-thiaziazole (2593-15-9)

Guidance literature:

In dichloromethane; water;

Reference yield:

sodium ethanolate (141-52-6) + 3-trichloromethyl-5-chloro-1,2,4-thiadiazole (5848-93-1) → 5-ethoxy-3-trichloromethyl-1,2,4-thiaziazole (2593-15-9)

Guidance literature:

In ethanol;

DOI:10.1021/jo01054a068

Reference yield:

→ 5-ethoxy-3-trichloromethyl-1,2,4-thiaziazole (2593-15-9)

Guidance literature:

Thiadiazol (I); NaOEt;

upstream raw materials:

sodium ethanolate

3-trichloromethyl-5-chloro-1,2,4-thiadiazole

potassium ethyl xanthogenate

Refernces

• 1、 -. "Delta1-pyrrolines used as pesticides". . . Retrieved 2008/06/13.
• 2、 -. "Glyoxylic acid derivatives". . . Retrieved 2008/06/13.