2-azido-1-phenylvinyl 3-cyclopentylpropionate

Base Information

• Chemical Name: 2-azido-1-phenylvinyl 3-cyclopentylpropionate
• CAS No.: 182251-94-1
• Molecular Formula: C₁₆H₁₉N₃O₂
• Molecular Weight: 285.346
• Mol file: 182251-94-1.mol

Synonyms:2-azido-1-phenylvinyl 3-cyclopentylpropionate

Chemical Property of 2-azido-1-phenylvinyl 3-cyclopentylpropionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-azido-1-phenylvinyl 3-cyclopentylpropionate

There total 2 articles about 2-azido-1-phenylvinyl 3-cyclopentylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopentanepropanoyl chloride (104-97-2) + 2-azido-1-phenylethan-1-one (1816-88-2) → 2-azido-1-phenylvinyl 3-cyclopentylpropionate (182251-94-1)

Guidance literature:

With diisopropylamine; In tetrahydrofuran; cyclohexane;

Reference yield:

2-azido-1-phenylethan-1-one (1816-88-2) → 2-azido-1-phenylvinyl 3-cyclopentylpropionate (182251-94-1)

Guidance literature:

2-azido-1-phenylethan-1-one; With lithium diisopropyl amide; at -78 ℃;

c-pentylethyl-COCl or (c-pentylethyl-CO)2O;

DOI:10.1016/S0960-894X(00)00277-8

Reference yield:

2-azido-1-phenylvinyl 3-cyclopentylpropionate (182251-94-1) → 2-(2-cyclopentylethyl)-5-phenyloxazole (182251-95-2)

Guidance literature:

With triethyl phosphite; In cyclohexane; Heating;

DOI:10.1016/S0960-894X(00)00277-8

upstream raw materials:

2-azido-1-phenylethan-1-one

cyclopentanepropanoyl chloride

Downstream raw materials:

2-(2-cyclopentylethyl)-5-phenyloxazole

4-[2-(2-cyclopentylethyl)oxazol-5-yl]benzenesulfonyl chloride

(R)-N-[4-[2-[[2-Hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[2-(2-cyclopentylethyl)oxazol-5-yl]benzenesulfonamide

(R)-N-[4-[2-[N-(1,1-Dimethylethoxycarbonyl)-N-[2-Hydroxy-2-(Pyridin-3-Yl)Ethyl]Amino]Ethyl]Phenyl]-4-[2-(2-Cyclopentylethyl)Oxazol-5-yl]Benzenesulfonamide

Refernces

• 1、 -. "SUBSTITUTED SULFONAMIDES AS SELECTIVE BETA3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY". . . Retrieved 2008/06/13.