2-Norbornanemethanol

Base Information

• Chemical Name: 2-Norbornanemethanol
• CAS No.: 5240-72-2
• Molecular Formula: C8H14 O
• Molecular Weight: 126.199
• European Community (EC) Number: 226-041-6
• NSC Number: 55693,53599
• DSSTox Substance ID: DTXSID70875762
• Nikkaji Number: J54.261J
• Mol file: 5240-72-2.mol

Synonyms:5240-72-2;2-NORBORNANEMETHANOL;Bicyclo[2.2.1]heptan-2-ylmethanol;Bicyclo[2.2.1]heptane-2-methanol;Norbornane-2-methanol;2-Norbornylmethanol;2-Norcamphanemethanol;2-(Hydroxymethyl)norbornane;2-Norcamphanylmethanol;CPC 1207;2-Norkamfanylmethanol;2-norbornane methanol;2-Norcamphane methanol;Experimental chemotherapeutant 1,207;CC 1207;EC-1207;2-Hydroxymethylnorbornane;2-Hydroxymethylnorcamphane;2-bicyclo[2.2.1]heptanylmethanol;NSC 53599;NSC 55693;2-Norkamfanylmethanol [Czech];Bicyclo(2.2.1)heptane-2-methanol;EINECS 226-041-6;2-Hydroxymethylbicyclo(2.2.1)heptane;BRN 2203428;2-(Hydroxymethyl)norcamphane;AI3-08982;2-(Hydroxymethyl)bicyclo[2.2.1]heptane;2-06-00-00062 (Beilstein Handbook Reference);WLN: L55 ATJ C1Q;2-Hydroxymethylbicyclo[2.2.1]heptane;Methanol, 2-norbornane-;SCHEMBL75491;DTXSID70875762;CPC-1207;NSC53599;NSC55693;Bicyclo(2,2,1)heptane-2-carbinol;bicyclo[2.2.1]hept-2-yl-methanol;Bicyclo[2.2.1]heptane-2-carbinol;Bicyclo[2.2.1]hheptane-2-methanol;NSC-53599;NSC-55693;(Bicyclo[2.2.1]hept-2-yl)methanol;AKOS009075809;Bicyclo[2.2.1]hept-2-ylmethanol #;{bicyclo[2.2.1]heptan-2-yl}methanol;LS-97109;FT-0622957;N0553;EN300-22337;A870994;Z147642452

Chemical Property of 2-Norbornanemethanol

Chemical Property:

• Vapor Pressure: 0.124mmHg at 25°C
• Refractive Index: n20/D 1.49(lit.)
• Boiling Point: 93-95 ºC (14 mmHg)
• PKA: 15.05±0.10(Predicted)
• Flash Point: 84 ºC
• PSA: 20.23000
• Density: 0.942
• LogP: 1.41490
• Water Solubility.: 999mg/L(temperature not stated)
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 126.104465066
• Heavy Atom Count: 9
• Complexity: 111

Purity/Quality:

98%,99%, ^*data from raw suppliers

Norbornane-2-methanol >95.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2CC1CC2CO

Technology Process of 2-Norbornanemethanol

There total 23 articles about 2-Norbornanemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-hydroxymethyl-2-norbornene (95-12-5) → exo-hydroxymethylnorbornane (5240-72-2)

Guidance literature:

With hydrogen; In ethanol;

DOI:10.1021/acs.jmedchem.6b00705

Reference yield: 71.0%

norbornane-2-carboxaldehyde (19396-83-9) → norbornan-2-ylmethyl norbornane-2-carboxylate (119337-06-3) + exo-hydroxymethylnorbornane (5240-72-2)

Guidance literature:

With diiron nonacarbonyl; In tetrahydrofuran; for 48h; Heating;

DOI:10.1021/jo00269a047

Reference yield: 68.0%

norbornane-2-carboxaldehyde (19396-83-9) → exo-hydroxymethylnorbornane (5240-72-2)

Guidance literature:

With diiron nonacarbonyl; In dibutyl ether; for 48h; Heating;

DOI:10.1021/jo00269a047

upstream raw materials:

2-Bicyclo<2.2.1>heptylmethyl acetate

methanol

norborn-2-ene

Methyl formate

Downstream raw materials:

2-iodomethyl-norbornane

Essigsaeure-<8,9,10-trinorbornan-2-endo-methyl>ester

C₂₄H₃₄O₃

norborn-2-ene

Refernces

• 1、 Beller, Matthias,Huang, Weiheng,Jackstell, Ralf,Jiao, Haijun,Tian, Xinxin. "Iridium-Catalyzed Domino Hydroformylation/Hydrogenation of Olefins to Alcohols: Synergy of Two Ligands". supporting information. . Retrieved 2022/01/13.
• 2、 Ali, Meher,Gual, Aitor,Ebeling, Guenter,Dupont, Jairton. "Ruthenium-catalyzed hydroformylation of alkenes by using carbon dioxide as the carbon monoxide source in the presence of ionic liquids". . p. 2224 - 2228. Retrieved 2014/08/18.