N,N-Dimethylformamide dipropyl acetal

Base Information

• Chemical Name: N,N-Dimethylformamide dipropyl acetal
• CAS No.: 6006-65-1
• Molecular Formula: C9H21NO2
• Molecular Weight: 175.271
• Hs Code.: 29225000
• European Community (EC) Number: 227-855-4
• DSSTox Substance ID: DTXSID60208787
• Nikkaji Number: J150.713C
• Wikidata: Q72470506
• Mol file: 6006-65-1.mol

Synonyms:N,N-Dimethylformamide dipropyl acetal;6006-65-1;N,N-dimethyl-1,1-dipropoxymethanamine;1,1-Dipropoxytrimethylamine;N,N-Dimethylformamide di-n-propyl acetal;N,N-DIMETHYLFORMAMIDEDIPROPYLACETAL;EINECS 227-855-4;N,N-Dimethylformamide dipropyl acetal for gc derivatization;(dipropoxymethyl)dimethylamine;Methanamine, N,N-dimethyl-1,1-dipropoxy-;Dimethyl(dipropoxymethyl)amine;SCHEMBL132624;dimethylformamide dipropyl acetal;NSLGQFIDCADTAS-UHFFFAOYSA-;DTXSID60208787;n,n-dimethylformamide dipropylacetal;MFCD00009374;N,N-Dimethyl(dipropoxy)methanamine #;AKOS024348828;N,N-Dimethylformamide dipropyl acetal, 97%;CS-0099674;D1301;FT-0629540;W-105281;N,N-Dimethylformamide Dipropyl Acetal [for Esterification];N,N-Dimethylformamide dipropyl acetal, for GC derivatization

Chemical Property of N,N-Dimethylformamide dipropyl acetal

Chemical Property:

• Appearance/Colour: Colorless liquid.
• Vapor Pressure: 1.12mmHg at 25°C
• Refractive Index: n20/D 1.409(lit.)
• Boiling Point: 175.9 °C at 760 mmHg
• PKA: 5.25±0.50(Predicted)
• Flash Point: 37.8 °C
• PSA: 21.70000
• Density: 0.887 g/cm³
• LogP: 1.68480
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Water Solubility.: It hydrolyzes with water.
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 175.157228913
• Heavy Atom Count: 12
• Complexity: 88.5

Purity/Quality:

99% ^*data from raw suppliers

N,N-Dimethylformamide dipropyl acetal ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC(N(C)C)OCCC
• Uses: N,N-Dimethylformamide di-n-propyl acetal, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.

Technology Process of N,N-Dimethylformamide dipropyl acetal

There total 5 articles about N,N-Dimethylformamide dipropyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propan-1-ol (71-23-8) + Vilsmeier reagent (3724-43-4,149409-22-3) → N,N-dimethylformamide dipropyl acetal (6006-65-1)

Guidance literature:

With sodium n-propoxide; In chloroform;

Reference yield:

1,1-dichloromethyl-N,N-dimethylamine (25818-74-0) + sodium n-propoxide (6819-41-6) → N,N-dimethylformamide dipropyl acetal (6006-65-1)

Guidance literature:

In propan-1-ol;

Reference yield:

Bis(dimethylamino)acetonitrile (2214-82-6) + sodium n-propoxide (6819-41-6) → N,N-dimethylformamide dipropyl acetal (6006-65-1)

Guidance literature:

In propan-1-ol;

upstream raw materials:

propan-1-ol

Vilsmeier reagent

1,1-dichloromethyl-N,N-dimethylamine

sodium n-propoxide

Downstream raw materials:

(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

3-(4-cyanobenzoyl) indolizine

propyl ester of dimethylcarbamic acid

propionaldehyde