3,5-Diiodo-4-hydroxybenzoic acid

Base Information Edit

Chemical Name:3,5-Diiodo-4-hydroxybenzoic acid
CAS No.:618-76-8
Molecular Formula:C7H4 I2 O3
Molecular Weight:389.916
Hs Code.:2918290000
European Community (EC) Number:210-562-0
NSC Number:1497
UNII:8C0QV5JK0D
DSSTox Substance ID:DTXSID1060685
Nikkaji Number:J87.192C
Wikidata:Q27270166
ChEMBL ID:CHEMBL83650
Mol file:618-76-8.mol

Synonyms:4-Hydroxy-3,5-diiodobenzoic acid;618-76-8;3,5-Diiodo-4-hydroxybenzoic acid;Ioxynic acid;Ioxynil acid;Benzoic acid, 4-hydroxy-3,5-diiodo-;M and B 10903;NSC 1497;4-Hydroxy-3,5-diiodo-benzoic acid;EINECS 210-562-0;UNII-8C0QV5JK0D;BRN 2212145;8C0QV5JK0D;CHEMBL83650;AI3-14923;BENZOIC ACID, 3,5-DIIODO-4-HYDROXY-;NSC-1497;4-10-00-00479 (Beilstein Handbook Reference);Ioxynil metabolite;MFCD00016532;SCHEMBL1613916;DTXSID1060685;4-Hydroxy-3,5-diiodobenzoicacid;NSC1497;3,5-di-iodo-4-hydroxybenzoic acid;3,5-Diiodo-4-hydroxy-benzoic acid;BDBM50145835;AKOS022171999;CS-W011729;AS-10550;LS-37096;MB-10903;3,5-DIIODO-4-HYDROXY BENZOIC ACID;M&B-10903;FT-0614624;A868608;AJ-087/41885658;Q27270166;18-76-8

Suppliers and Price of 3,5-Diiodo-4-hydroxybenzoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,5-Diiodo-4-hydroxybenzoicAcid
1 g
$ 60.00

Medical Isotopes, Inc.
3,5-Diiodo-4-hydroxybenzoicAcid
100 mg
$ 640.00

Matrix Scientific
4-Hydroxy-3,5-diiodobenzoic acid 97%
1g
$ 39.00

Matrix Scientific
4-Hydroxy-3,5-diiodobenzoic acid 97%
10g
$ 197.00

Crysdot
4-Hydroxy-3,5-diiodobenzoicacid 97%
100g
$ 324.00

Chemenu
4-Hydroxy-3,5-diiodobenzoicacid 95+%
100g
$ 303.00

Biosynth Carbosynth
3,5-Diiodo-4-hydroxybenzoic acid
50 g
$ 315.00

Biosynth Carbosynth
3,5-Diiodo-4-hydroxybenzoic acid
100 g
$ 525.00

Biosynth Carbosynth
3,5-Diiodo-4-hydroxybenzoic acid
25 g
$ 185.00

Biosynth Carbosynth
3,5-Diiodo-4-hydroxybenzoic acid
5 g
$ 60.00

Total 29 raw suppliers

Chemical Property of 3,5-Diiodo-4-hydroxybenzoic acid Edit

Chemical Property:

Vapor Pressure:2.19E-05mmHg at 25°C
Melting Point:275°C (dec.)
Boiling Point:346.4°C at 760 mmHg
PKA:3.87±0.10(Predicted)
Flash Point:163.3°C
PSA：57.53000
Density:2.697g/cm³
LogP:2.29960
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Light Sensitive
Solubility.:Dichloromethane, Ethyl Acetate
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:389.82499
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

3,5-Diiodo-4-hydroxybenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes:R36/37/38:Irritating to eyes, respiratory system and skin.;
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1I)O)I)C(=O)O
Uses 3,5-DIIODO-4-HYDROXYBENZOIC ACID is used in the preparation of Thyroid hormone analogues.

Technology Process of 3,5-Diiodo-4-hydroxybenzoic acid

There total 17 articles about 3,5-Diiodo-4-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.4%

: 99-96-7
4-hydroxy-benzoic acid

: 618-76-8
3,5-diiodo-4-hydroxybenzoic acid

Guidance literature:: With sulfuric acid; Iodine monochloride; In water; at 80 ℃;
DOI:10.3762/bjoc.10.167

Reference yield:

: 99-96-7
4-hydroxy-benzoic acid

: 37470-46-5
4-hydroxy-3-iodobenzoic acid

: 618-76-8
3,5-diiodo-4-hydroxybenzoic acid

Guidance literature:: With ethanol; iodine; mercury(II) oxide;
DOI:10.1557/JMR.2000.0081

Reference yield:

: 29289-13-2
2-iodo-4-methylaniline

: 618-76-8
3,5-diiodo-4-hydroxybenzoic acid

Guidance literature:: Multi-step reaction with 4 steps

2: potassium permanganate; magnesium sulfate

3: concentrated hydrochloric acid

4: Diazotization

With hydrogenchloride; potassium permanganate; magnesium sulfate;