velutin

Base Information

• Chemical Name: velutin
• CAS No.: 25739-41-7
• Molecular Formula: C17H14 O6
• Molecular Weight: 314.295
• Hs Code.: 2914509090
• UNII: CT1Q4E0I0W
• DSSTox Substance ID: DTXSID90180421
• Nikkaji Number: J146.867G
• Wikipedia: Velutin
• Wikidata: Q15427946
• Metabolomics Workbench ID: 24136
• ChEMBL ID: CHEMBL508292
• Mol file: 25739-41-7.mol

Synonyms:Flavone,4',5-dihydroxy-3',7-dimethoxy- (6CI,8CI); 3',7-Dimethoxy-4',5-dihydroxyflavone;3',7-Dimethylluteolin; 4',5-Dihydroxy-3',7-dimethoxyflavone;5,4'-Dihydroxy-7,3'-dimethoxyflavone; 7,3'-Di-O-methylluteoline; Chrysoeriol7-methyl ether; DR 9606128; Flavoyadorigenin B; Luteolin 3',7-dimethyl ether;Luteolin 7,3'-dimethyl ether; Velutin

Chemical Property of velutin

Chemical Property:

• Vapor Pressure: 1.76E-13mmHg at 25°C
• Melting Point: 298 °C
• Boiling Point: 567.5°C at 760 mmHg
• PKA: 6.33±0.40(Predicted)
• Flash Point: 213.1°C
• PSA: 89.13000
• Density: 1.402g/cm³
• LogP: 2.88840
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 314.07903816
• Heavy Atom Count: 23
• Complexity: 476

Purity/Quality:

99%, ^*data from raw suppliers

Velutin| ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O
• Uses: Velutin is a flavone isolated from the aerial parts of Leucas stelligera.

Technology Process of velutin

There total 23 articles about velutin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-(benzyloxy)-2-(4-(benzyloxy)-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one → velutin (25739-41-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In tetrahydrofuran; methanol; at 20 ℃; for 12h;

DOI:10.3390/molecules26103033

Reference yield:

2‐(4‐hydroxy‐3‐methoxyphenyl)‐5,7‐dimethoxy‐4H‐chromen‐4‐one (1239-68-5) → 7,4′-dihydroxy-5,3′-dimethoxyflavone (62346-14-9) + velutin (25739-41-7) + 5-hydroxy-3',4',7-trimethoxyflavone (29080-58-8) + 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one (855-97-0)

Guidance literature:

at 300 ℃; for 0.0333333h; Mechanism; transmethylation reaction;

Reference yield:

5,4'-dihydroxy-7,3'-dimethoxyflavone-4'-O-β-D-xylopyranosyl-(2a→1b)-2a-O-β-D-xylopyranosyl-(2b→1c)-2b-O-β-D-xylopyranosyl-2c-octadecanoate (1449692-19-6) → D-xylose (58-86-6) + velutin (25739-41-7) + stearic acid (57-11-4)

Guidance literature:

5,4'-dihydroxy-7,3'-dimethoxyflavone-4'-O-β-D-xylopyranosyl-(2a→1b)-2a-O-β-D-xylopyranosyl-(2b→1c)-2b-O-β-D-xylopyranosyl-2c-octadecanoate; With hydrogenchloride; In ethanol; water; at 70 - 80 ℃;

With hydrogenchloride; In ethanol; water;

DOI:10.1021/jf402145u

upstream raw materials:

(-)-5-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-7-methoxy-chroman-4-one

7,4′-dihydroxy-5,3′-dimethoxyflavone

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

2‐(4‐hydroxy‐3‐methoxyphenyl)‐5,7‐dimethoxy‐4H‐chromen‐4‐one

Downstream raw materials:

2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

5-acetoxy-2-(4-acetoxy-3-methoxy-phenyl)-7-methoxy-chromen-4-one

Refernces

• 1、 -. "Process for preparing flavonoid derivatives and the intermediate thereof". . . Retrieved 2020/10/03.
• 2、 Ahmad, Ateeque,Kim, Seung-Hyun,Ali, Mohd,Park, Inmyoung,Kim, Jin-Seog,Kim, Eun-Hye,Lim, Ju-Jin,Kim, Seul-Ki,Chung, Ill-Min. "New chemical constituents from oryza sativa straw and their algicidal activities against blue-green algae". . p. 8039 - 8048. Retrieved 2013/09/23.