Teriparatide acetate

Base Information

• Chemical Name: Teriparatide acetate
• CAS No.: 52232-67-4
• Molecular Formula: C181H291N55O51S2
• Molecular Weight: 4177.77
• Hs Code.: 2937190000
• Mol file: 52232-67-4.mol

Synonyms:(1-34)-Humanparathormone;(1-34)-Human parathyroid hormone;22: PN: US6110892 SEQID: 22 unclaimed protein;32: PN: WO2008068487 SEQID: 32 claimedprotein;692: PN: WO2004005342PAGE: 46 claimed protein;7:PN: WO0031137 SEQID: 8 unclaimed protein;93: PN: WO0069900 SEQID: 272 unclaimed protein;Forsteo;Forteo;HPTH-(1-34);Human PTH(1-34);Human parathormone(1-34);Human parathyroidhormone-(1-34);LY 333334;Parathar;pTH (1-34) (human);

Chemical Property of Teriparatide acetate

Chemical Property:

• Appearance/Colour: powder
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: −20°C
• Solubility.: DMSO (Slightly), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

ParathyroidHormoneFragment(1-34) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A fragment of human parathyroid hormone (hPTH) peptide sequence containing the 34 N-terminal residues of hPTH. This fragment was also found to be an agonist at PTH1 and PTH2 receptors.
• Clinical Use: In 2002, the U.S. FDA approved teriparatide for the treatment of postmenopausal osteoporosis in patients who have a high risk of fracture as well as to increase bone mass in men with primary or hypogonadal osteoporosis who have a high risk of fracture. Teriparatide is recombinant human PTH 1-34, the biologically active portion of the endogenously produced preprohormone. Unlike the bisphosphonates, which are classified as bone restorative agents, teriparatide is the first approved bone-forming agent. Bone formation is possible because of the ability of this agent to increase the number of osteoblasts. Although teriparatide enhances the function of both osteoclasts and osteoblasts, the exposure incidence dictates its effect on the skeleton.