Carbofuran

Base Information Edit

Chemical Name:Carbofuran
CAS No.:1563-66-2
Molecular Formula:C12H15NO3
Molecular Weight:221.256
Hs Code.:29329990
European Community (EC) Number:216-353-0
ICSC Number:0122
NSC Number:167822
UN Number:2757
UNII:SKF77S6Y67
DSSTox Substance ID:DTXSID9020249
Nikkaji Number:J3.369C
Wikipedia:Carbofuran
Wikidata:Q423136
NCI Thesaurus Code:C163636
Metabolomics Workbench ID:45089
ChEMBL ID:CHEMBL416081
Mol file:1563-66-2.mol

Synonyms:Bayer 70143;Carbofuran;Furadan;NIA 10242;NIA-10242;NIA10242

Suppliers and Price of Carbofuran

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Carbofuran
5g
$ 75.00

Sigma-Aldrich
Carbofuran PESTANAL
250mg
$ 28.30

Sigma-Aldrich
Carbofuran 98%
5g
$ 68.40

Medical Isotopes, Inc.
Carbofuran
1 g
$ 610.00

Cayman Chemical
Carbofuran
100mg
$ 48.00

Cayman Chemical
Carbofuran
50mg
$ 25.00

AHH
Carbofuran 98%
10g
$ 390.00

Total 2 raw suppliers

Chemical Property of Carbofuran Edit

Chemical Property:

Appearance/Colour:odorless white crystalline solid
Vapor Pressure:0.000502mmHg at 25°C
Melting Point:150-153 °C(lit.)
Refractive Index:1.525
Boiling Point:313.3 °C at 760 mmHg
PKA:12.28±0.46(Predicted)
Flash Point:143.3 °C
PSA：47.56000
Density:1.137 g/cm³
LogP:2.50920
Storage Temp.:0-6°C
Solubility.:Methylene chloride (>200 g/L), 2-propanol (20–50 g/L) (Worthing and Hance, 1991)
Water Solubility.:Slightly soluble. 0.07 g/100 mL
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:277
Transport DOT Label:Poison

Purity/Quality:: Carbofuran ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+,N,T
Hazard Codes:T+,N,T
Statements: 26/28-50/53
Safety Statements: 36/37-45-60-61-1/2

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Pesticides -> Carbamate Insecticides
Canonical SMILES:CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C
Inhalation Risk:Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
Effects of Short Term Exposure:The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Cholinesterase inhibition. The effects may be delayed. Exposure could cause death. Medical observation is indicated.
Effects of Long Term Exposure:Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Description Carbofuran is a broad-spectrum carbamate insecticide and nematocide. It is an odourless, white crystalline solid. On heating, its breakdown can release toxic fumes and irritating or poisonous gases. It is sparingly soluble in water but very soluble in acetone, acetonitrile, benzene, and cyclohexone. The liquid formulations of carbofuran are classified as restricted use pesticides (RUP) because of their acute oral and inhalation toxicity to humans. Granular formulations are also classified as RUP. In fact, carbofuran was first registered in the United States in 1969 and classified as RUP. Exposure to heat breaks down carbofuran, with the release of toxic fumes. Carbofuran is used for the control of soil-dwelling and foliar-feeding insects. It is also used for the control of aphids, thrips, and nematodes that attack vegetable, ornamental plants, crops of sunflower, potatoes, peanuts, soybeans, sugar cane, cotton, rice, and variety of other crops. Carbofuran is another systemic insecticidal/nematicidal carbamate available in granular and liquid formulations. Because use of carbofuran granules was associated with bird kills, the U.S. Environmental Protection Agency (EPA) prohibited the use of carbofuran granules in 1994.
Uses Carbofuran is a broad-spectrum N-methyl carbamate sold under the trade name Furadan. First registered in 1969, it is used to control a variety of insect pests on field, fruit, and vegetable crops. Carbofuran is not used in residential settings or food-handling establishments. The chemical is a restricted use pesticide with nearly 1 million pounds of active ingredient almost exclusively used on corn, alfalfa, and potatoes (U.S. EPA, 2006a). Broad-spectrum, systemic insecticide, nematocide and acaricide applied in soil to control soil insects and nematodes or on foliage to control insects and mites. Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Carbofuran is used to control soil-dwelling insect pests and nematodes in a wide range of crops.

Technology Process of Carbofuran

There total 14 articles about Carbofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%