2,4-Diaminophenol

Base Information

• Chemical Name: 2,4-Diaminophenol
• CAS No.: 95-86-3
• Molecular Formula: C6H8 N2 O
• Molecular Weight: 124.142
• Hs Code.: 2922299090
• European Community (EC) Number: 202-459-4
• UNII: H691WBT7OS
• DSSTox Substance ID: DTXSID7043748
• Nikkaji Number: J53.750K
• Wikipedia: Amidol
• Wikidata: Q3297000
• ChEMBL ID: CHEMBL2924225
• Mol file: 95-86-3.mol

Synonyms:2,4-diaminophenol;2,4-diaminophenol dihydrochloride;2,4-diaminophenol hydrochloride;amidol

Chemical Property of 2,4-Diaminophenol

Chemical Property:

• Vapor Pressure: 2.68E-05mmHg at 25°C
• Melting Point: 79°C (rough estimate)
• Refractive Index: 1.5745 (estimate)
• Boiling Point: 347.4°Cat760mmHg
• PKA: 10.02±0.18(Predicted)
• Flash Point: 163.9°C
• PSA: 72.27000
• Density: 1.343g/cm³
• LogP: 1.71900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 124.063662883
• Heavy Atom Count: 9
• Complexity: 97.1

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Diaminophenol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1N)N)O
• Uses: Used in dye manufacture, in hair and fur dyeing, and in tests for formaldehyde and ammonia.

Technology Process of 2,4-Diaminophenol

There total 22 articles about 2,4-Diaminophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,4-Dinitrophenol (51-28-5) → 2,4-diaminophenol (95-86-3)

Guidance literature:

With sodium tetrahydroborate; pyrographite; In tetrahydrofuran; water; at 50 - 60 ℃; for 5h;

DOI:10.1080/00397910600764709

Reference yield:

sulfuric acid (7664-93-9) + acetic acid-(2,4-bis-phenylazo-phenyl ester) → 2,4-diaminophenol (95-86-3) + aniline (62-53-3) + Acetanilid (103-84-4)

Guidance literature:

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 2-(4-bromo-phenylazo)-4-nitro-phenol (138507-63-8) → 2,4-diaminophenol (95-86-3) + 4-bromo-aniline (106-40-1)

Guidance literature:

upstream raw materials:

meta-dinitrobenzene

2,4-Dinitrophenol

2-nitro-4-(4'-sulfophenylazo)-phenol

3-nitro-aniline

Downstream raw materials:

5-amino-2-(2-bromophenyl) benzoxazole

2-(4-methoxyphenyl)benzo[d]oxazol-5-amine

2-(4-methylphenyl)-5-aminobenzoxazole

2-(2-chlorophenyl)benzo[d]oxazol-5-amine

Refernces

• 1、 Giri, Arkaprabha,Patil, Niraj Nitish,Patra, Abhijit. "Porous noria polymer: a cage-to-network approach toward a robust catalyst for CO2fixation and nitroarene reduction". . p. 4404 - 4407. Retrieved 2021.
• 2、 Acharya, Anubhab,Kumar, Amit,Lee, In Su. "Yolk@Shell Nanoreactors Carrying a Cluster of Metal Nanocrystals Stabilized Inside the Hollow Carbon Shell". . p. 915 - 918. Retrieved 2021.
• 3、 Harikrishnan, Kaloor S.,Krishnan, Nithiyanandan,Kumar, Nilima Manoj,Krishna, Anusree,Raj, Gowtham,Perumal, Devanathan,Kalathil, Jemshiya,Krishna, Jithu,Varghese, Reji. "Galactose Grafted Two-Dimensional Nanosheets as a Scaffold for the In Situ Synthesis of Silver Nanoparticles: A Potential Catalyst for the Reduction of Nitroaromatics". . p. 14100 - 14107. Retrieved 2021/09/06.