N-acetyl-5-bromo-4-chloroanthranilic acid

Base Information

• Chemical Name: N-acetyl-5-bromo-4-chloroanthranilic acid
• CAS No.: 1607828-44-3
• Molecular Formula: C₉H₇BrClNO₃
• Molecular Weight: 292.516
• Mol file: 1607828-44-3.mol

Synonyms:N-acetyl-5-bromo-4-chloroanthranilic acid

Chemical Property of N-acetyl-5-bromo-4-chloroanthranilic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-acetyl-5-bromo-4-chloroanthranilic acid

There total 2 articles about N-acetyl-5-bromo-4-chloroanthranilic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

N-(4-bromo-5-chloro-2-methylphenyl)-acetamide (1607828-43-2) → N-acetyl-5-bromo-4-chloroanthranilic acid (1607828-44-3)

Guidance literature:

With potassium permanganate; magnesium sulfate; In water; for 5.5h; Reflux;

DOI:10.1002/ejoc.201301198

Reference yield:

N-(5-chloro-2-methylphenyl)acetamide (5900-55-0) → N-acetyl-5-bromo-4-chloroanthranilic acid (1607828-44-3)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / acetic acid / 5 h / 20 °C / Cooling with ice

2: potassium permanganate; magnesium sulfate / water / 5.5 h / Reflux

With potassium permanganate; bromine; magnesium sulfate; In water; acetic acid;

DOI:10.1002/ejoc.201301198

Reference yield: 94.0%

N-acetyl-5-bromo-4-chloroanthranilic acid (1607828-44-3) → 2-amino-5-bromo-4-chlorobenzene carboxylic acid (50419-88-0)

Guidance literature:

With water; sodium hydroxide; for 4h; Reflux;

DOI:10.1002/ejoc.201301198

upstream raw materials:

N-(4-bromo-5-chloro-2-methylphenyl)-acetamide

N-(5-chloro-2-methylphenyl)acetamide

Downstream raw materials:

2-amino-5-bromo-4-chlorobenzene carboxylic acid

5-bromo-4-chloro-N-[(allyloxycarbonyl)methyl]anthranilic acid allyl ester

(5-bromo-6-chloroindol-3-yl)-β-D-galactopyranoside

Refernces