γGlu-L-Cys-γGlu-L-Cys-Gly-OH

Base Information

• Chemical Name: γGlu-L-Cys-γGlu-L-Cys-Gly-OH
• CAS No.: 95014-75-8
• Molecular Formula: C18H29N5O10S2
• Molecular Weight: 539.588
• Mol file: 95014-75-8.mol

Synonyms:γGlu-Cys-γGlu-Cys-Gly;Cadystin (γEC)2G;H-(γ-Glu-Cys)2-Gly-OH;(γ-Glu-Cys)2-Gly;PC2;

Chemical Property of γGlu-L-Cys-γGlu-L-Cys-Gly-OH

Chemical Property:

• PSA: 331.92000
• LogP: -1.17800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of γGlu-L-Cys-γGlu-L-Cys-Gly-OH

There total 18 articles about γGlu-L-Cys-γGlu-L-Cys-Gly-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

H-<γ-Glu-Cys(StBu)>2-Gly-OH (138901-81-2) → H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B <2>) (95014-75-8)

Guidance literature:

With ammonium acetate; 2-hydroxyethanethiol; for 2h; Ambient temperature;

Reference yield: 69.3%

Boc-<γ-Glu(OBzl)-Cys(MBzl)>2-Gly-OBzl (131574-48-6) → H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B <2>) (95014-75-8)

Guidance literature:

With methyl-phenyl-thioether; hydrogen fluoride; 3-methyl-phenol; at 0 ℃; for 1h;

DOI:10.1248/cpb.38.2364

Reference yield: 67.0%

Tr-L-Glu-OBn> (95014-77-0) → H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B <2>) (95014-75-8)

Guidance literature:

With hydrogen fluoride; ethane-1,2-dithiol; methoxybenzene; at 0 ℃; for 1h;

upstream raw materials:

Boc-<γ-Glu(OBzl)-Cys(MBzl)>2-Gly-OBzl

Tr-L-Glu-OBn>

H-<γ-Glu-Cys(StBu)>2-Gly-OH

GLUTATHIONE

Downstream raw materials:

N-L-γ-glutamyl-L-cysteine

Refernces

• 1、 -. "Cosmetic Composition Comprising Phytochelatin". Paragraph 0042; 0053-0066. . Retrieved 2021/05/18.
• 2、 Zeng, Weiguang,Hemmasi, Bahram. "Solution Synthesis of Phytochelatins, Isopeptides from the Plant Kingdom". . p. 311 - 316. Retrieved 2007/10/02.