allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate

Base Information

• Chemical Name: allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate
• CAS No.: 122617-94-1
• Molecular Formula: C₁₁H₁₅FO₃
• Molecular Weight: 214.237
• Mol file: 122617-94-1.mol

Synonyms:allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate

Chemical Property of allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate

There total 1 articles about allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

allyl 3-methyl-2-oxocyclohexanonecarboxylate (75265-74-6) → allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate (122617-94-1)

Guidance literature:

With sodium hydride; 1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate; In tetrahydrofuran; at 0 ℃; for 2h;

DOI:10.1016/S0040-4020(01)80770-5

Reference yield: 66.0%

allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate (122617-94-1) → 2-allyl-2-fluoro-6-methylcyclohexanone (122617-98-5)

Guidance literature:

tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; for 1h; Heating;

DOI:10.1246/cl.1999.577

Reference yield: 61.0%

allyl 1-fluoro-3-methyl-2-oxocyclohexanonecarboxylate (122617-94-1) → 2-fluoro-6-methyl-2-cyclohexenone (122617-99-6)

Guidance literature:

tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triphenylphosphine; In acetonitrile; for 2h; Heating;

DOI:10.1246/cl.1999.577 DOI:10.1016/S0040-4020(01)80770-5

upstream raw materials:

allyl 3-methyl-2-oxocyclohexanonecarboxylate

Downstream raw materials:

2-fluoro-6-methyl-2-cyclohexenone

2-allyl-2-fluoro-6-methylcyclohexanone

Refernces