Technology Process of C33H40Cl2F2N8O3
There total 3 articles about C33H40Cl2F2N8O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tert.-butylhydroperoxide; trifluoroacetic acid; zinc(II) chloride;
In
water; dimethyl sulfoxide;
at 50 ℃;
for 25h;
Cooling with ice;
DOI:10.1021/ja407739y
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydride; ethanethiol / tetrahydrofuran / 12 h / 0 °C / Inert atmosphere
2: zinc(II) chloride; tert.-butylhydroperoxide; trifluoroacetic acid / water; dimethyl sulfoxide / 25 h / 50 °C / Cooling with ice
With
tert.-butylhydroperoxide; sodium hydride; trifluoroacetic acid; ethanethiol; zinc(II) chloride;
In
tetrahydrofuran; water; dimethyl sulfoxide;
DOI:10.1021/ja407739y
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium azide; sodium iodide / N,N-dimethyl-formamide / 10 h / 65 °C / Inert atmosphere
2: sodium hydride; ethanethiol / tetrahydrofuran / 12 h / 0 °C / Inert atmosphere
3: zinc(II) chloride; tert.-butylhydroperoxide; trifluoroacetic acid / water; dimethyl sulfoxide / 25 h / 50 °C / Cooling with ice
With
tert.-butylhydroperoxide; sodium azide; sodium hydride; trifluoroacetic acid; ethanethiol; sodium iodide; zinc(II) chloride;
In
tetrahydrofuran; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ja407739y
