ethyl 2-(4-bromophenoxy)-2-methylbutanoate

Base Information

• Chemical Name: ethyl 2-(4-bromophenoxy)-2-methylbutanoate
• CAS No.: 28139-26-6
• Molecular Formula: C₁₃H₁₇BrO₃
• Molecular Weight: 301.18
• Mol file: 28139-26-6.mol

Synonyms:ethyl 2-(4-bromophenoxy)-2-methylbutanoate

Chemical Property of ethyl 2-(4-bromophenoxy)-2-methylbutanoate

Chemical Property:

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Technology Process of ethyl 2-(4-bromophenoxy)-2-methylbutanoate

There total 1 articles about ethyl 2-(4-bromophenoxy)-2-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ ethyl 2-(4-bromophenoxy)-2-methylbutanoate (28139-26-6)

Guidance literature:

/BRN= 755060/, p-Bromphenol, NaH;

Reference yield: 84.0%

ethyl 2-(4-bromophenoxy)-2-methylbutanoate (28139-26-6) + bis(pinacol)diborane (73183-34-3) → ethyl 2-methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)butanoate

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jacs.8b00380

Reference yield: 60.0%

ethyl 2-(4-bromophenoxy)-2-methylbutanoate (28139-26-6) + para-Chlorobenzyl alcohol (873-76-7) → beclobrate (55937-99-0)

Guidance literature:

ethyl 2-(4-bromophenoxy)-2-methylbutanoate; para-Chlorobenzyl alcohol; With cobalt(II) phthalocyanine; N-ethyl-N,N-diisopropylamine; zinc; Methanesulfonic anhydride; In N,N-dimethyl acetamide; at 20 ℃; for 1h;

With nickel(II) bromide trihydrate; at 20 ℃;

DOI:10.1039/c4sc03106g

Downstream raw materials:

beclobrate