Decylamine

Base Information

• Chemical Name: Decylamine
• CAS No.: 2016-57-1
• Molecular Formula: C10H23N
• Molecular Weight: 157.299
• Hs Code.: 29211990
• European Community (EC) Number: 217-957-7
• UNII: M9KKQ6ZZG9
• DSSTox Substance ID: DTXSID2022171
• Nikkaji Number: J7.849B
• Wikidata: Q5493262
• Metabolomics Workbench ID: 78518
• ChEMBL ID: CHEMBL109819
• Mol file: 2016-57-1.mol

Synonyms:decylamine;decylammonium chloride

Chemical Property of Decylamine

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 0.107mmHg at 25°C
• Melting Point: 12-14 °C(lit.)
• Refractive Index: n20/D 1.436(lit.)
• Boiling Point: 221.403 °C at 760 mmHg
• PKA: 10.64(at 25℃)
• Flash Point: 85.556 °C
• PSA: 26.02000
• Density: 0.797 g/cm³
• LogP: 3.78610
• Storage Temp.: room temp
• Solubility.: Chloroform, Ethyl Acetate
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 8
• Exact Mass: 157.183049738
• Heavy Atom Count: 11
• Complexity: 61.9

Purity/Quality:

99% ^*data from raw suppliers

1-Decylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 22-24-34-20/22
• Safety Statements: 26-36/37/39-45

MSDS Files:

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCCCCCCCCCN
• Uses: 1-Decylamine is a intermediate forming the phosphatidylcholine-decylamine liposomal membranes. Decylamine was used in the synthesis of dynole 2-24 series by undergoing reductive amination with 1-(3-(dimethylamino)propyl)-1H-indole-3-carbaldehyde. It was also used as a coordinating solvent to thermolyse the lead piperidine and lead tetrahydroquinoline dithiocarbamate (DTC) complexes.

Technology Process of Decylamine

There total 42 articles about Decylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(benzyloxycarbonyl)decylamine → 1-aminodecane (2016-57-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 100 ℃; under 37503.8 Torr; Reagent/catalyst; Flow reactor;

DOI:10.1016/j.tet.2014.05.038

Reference yield: 97.0%

n-decanenitrile (1975-78-6) → 1-aminodecane (2016-57-1)

Guidance literature:

With sodium tetrahydroborate; In water; at 100 ℃; for 8h; pH=5.5;

DOI:10.1002/cctc.201300984

Reference yield: 97.0%

1-nitrodecane (4609-87-4) → 1-aminodecane (2016-57-1)

Guidance literature:

With hydrogen; at 100 ℃; for 12h; under 7500.75 Torr; Sealed tube; Autoclave;

DOI:10.1002/cctc.202100045

upstream raw materials:

decyl chloride

n-decanenitrile

1-decanoic acid

decanamide

Downstream raw materials:

N-decyl-succinimide

dec-1-ylurea

1-decyl-5-oxo-pyrrolidine-3-carboxylic acid

n-decanenitrile

Refernces

• 1、 Takita et al.. "". . p. 3699. Retrieved 1976.
• 2、 Kiuchi,Miyashita,Tsuda,Kondo,Yoshimura. "Studies on crude drugs effective on visceral larva migrans. I. Identification of larvicidal principles in betel nuts". . p. 2880 - 2886. Retrieved 1987.
• 3、 Yamada, Tsuyoshi,Park, Kwihwan,Furugen, Chikara,Jiang, Jing,Shimizu, Eisho,Ito, Naoya,Sajiki, Hironao. "Highly Selective Hydrogenative Conversion of Nitriles into Tertiary, Secondary, and Primary Amines under Flow Reaction Conditions". . . Retrieved 2021/12/13.
• 4、 Unglaube, Felix,Kreyenschulte, Carsten Robert,Mejía, Esteban. "Development and Application of Efficient Ag-based Hydrogenation Catalysts Prepared from Rice Husk Waste". . p. 2583 - 2591. Retrieved 2021/04/09.