C₂₂H₂₄O₅

Base Information

• Chemical Name: C₂₂H₂₄O₅
• CAS No.: 1419777-75-5
• Molecular Formula: C₂₂H₂₄O₅
• Molecular Weight: 368.43
• Mol file: 1419777-75-5.mol

Synonyms:C₂₂H₂₄O₅

Chemical Property of C₂₂H₂₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄O₅

There total 9 articles about C₂₂H₂₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C32H31NO7 (1419777-69-7) → C22H24O5 (1419777-75-5)

Guidance literature:

With methanol; lithium borohydride; In tetrahydrofuran; diethyl ether; for 5h;

DOI:10.1021/ol303482k

Reference yield:

eugenin (480-34-2) → C22H24O5 (1419777-75-5)

Guidance literature:

Multi-step reaction with 9 steps

1.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetone / 24 h / Reflux

2.1: 2 h / 200 °C

3.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetone / 24 h / Reflux

4.1: (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II) / tetrahydrofuran / 3 h / Reflux

5.1: 2,6-dimethylpyridine; osmium(VIII) oxide; sodium periodate / 1,4-dioxane; water; tert-butyl alcohol / 0.5 h

6.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 0.08 h / 0 °C

7.1: phosphorus tribromide / tetrahydrofuran; dichloromethane / 4.5 h / 0 °C

8.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C

8.2: 0.5 h / -78 °C

9.1: methanol; lithium borohydride / tetrahydrofuran; diethyl ether / 5 h

With 2,6-dimethylpyridine; methanol; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; lithium borohydride; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); sodium hexamethyldisilazane; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; water; acetone; tert-butyl alcohol;

DOI:10.1021/ol303482k

Reference yield:

eugenin (1013-69-0) → C22H24O5 (1419777-75-5)

Guidance literature:

Multi-step reaction with 10 steps

1.1: potassium carbonate / acetone / 12 h / 20 °C

2.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetone / 24 h / Reflux

3.1: 2 h / 200 °C

4.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetone / 24 h / Reflux

5.1: (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II) / tetrahydrofuran / 3 h / Reflux

6.1: 2,6-dimethylpyridine; osmium(VIII) oxide; sodium periodate / 1,4-dioxane; water; tert-butyl alcohol / 0.5 h

7.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 0.08 h / 0 °C

8.1: phosphorus tribromide / tetrahydrofuran; dichloromethane / 4.5 h / 0 °C

9.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C

9.2: 0.5 h / -78 °C

10.1: methanol; lithium borohydride / tetrahydrofuran; diethyl ether / 5 h

With 2,6-dimethylpyridine; methanol; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; lithium borohydride; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); sodium hexamethyldisilazane; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; water; acetone; tert-butyl alcohol;

DOI:10.1021/ol303482k

upstream raw materials:

eugenin

eugenin

C₁₄H₁₄O₄

C₁₄H₁₄O₄

Downstream raw materials:

C₂₂H₂₂O₅

C₂₃H₂₄O₅

C₃₃H₄₆O₇Si

C₃₃H₄₆O₇Si

Refernces