1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide

Base Information Edit

Chemical Name:1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide
CAS No.:4747-99-3
Molecular Formula:C16H17 N O4
Molecular Weight:287.315
Hs Code.:
European Community (EC) Number:630-581-1
NSC Number:118071
UNII:D7HN447UC9
Mol file:4747-99-3.mol

Synonyms:16659-88-4;(+/-)-Tetrahydropapaveroline hydrobromide;1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide;Tetrahydropapaveroline hydrobromide;THPV HBr;NSC-118071;1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrobromide;D7HN447UC9;Norlaudanosoline hydrobromide;6,7-Isoquinolinediol, 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydro-, hydrobromide (1:1);Bromhydrate de tetrahydropapaveroline;6,7-ISOQUINOLINEDIOL, 1-((3,4-DIHYDROXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO-, HYDROBROMIDE (1:1);ST056944;1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol Hydrobromide;C16H17NO4.BrH;SCHEMBL3276906;1,3,4-Tetrahydropapaveroline HBr;C16-H17-N-O4.Br-H;NSC118071;AKOS022181284;1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol, bromi de;EN300-27660;Papaveroline,2,3,4-tetrahydro-, hydrobromide;(+/-)-TETRAHYDROPAPAVEROLINEHYDROBROMIDE;6,7-Isoquinolinediol, 1-((3,4-dihydroxyphenyl)methyl)-1,2,3,4-tetrahydro-, HBr (9CI)

Suppliers and Price of 1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(+/-)-TETRAHYDRO PAPAVEROLINE 95.00%
5MG
$ 500.37

Total 2 raw suppliers

Chemical Property of 1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide Edit

Chemical Property:

Boiling Point:573.2°Cat760mmHg
PKA:9.71±0.40(Predicted)
Flash Point:235.1°C
PSA：92.95000
Density:1.406g/cm³
LogP:2.26730
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:367.04192
Heavy Atom Count:22
Complexity:353

Purity/Quality:

99% ^*data from raw suppliers

(+/-)-TETRAHYDRO PAPAVEROLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC(=C(C=C3)O)O.Br

Technology Process of 1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide

There total 14 articles about 1-(3,4-Dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 5707-55-1
3,4-Dihydroxyphenylacetaldehyde

: 62-31-7
dopamine hydrochloride

: 4747-99-3
Norlaudanosolin

Guidance literature:: With potassium phosphate; In water; acetonitrile; at 50 ℃; for 12h; pH=6;
DOI:10.1039/c4gc02325k

Reference yield: 28.0%

: 51-61-6
dopamine

: 4747-99-3
Norlaudanosolin

Guidance literature:: With pyridoxal 5'-phosphate; transaminase from chromobacterium violaceum; sodium pyruvate; sodium L-ascorbate; In aq. phosphate buffer; acetonitrile; at 37 ℃; for 10h; pH=7.5; Enzymatic reaction;
DOI:10.1002/anie.201902761