Fenclonine

Base Information Edit

Chemical Name:Fenclonine
CAS No.:7424-00-2
Deprecated CAS:1991-78-2
Molecular Formula:C9H10ClNO2
Molecular Weight:199.637
Hs Code.:29224985
European Community (EC) Number:217-874-6,231-051-9
NSC Number:77370
UNII:R5J7E3L9SP
DSSTox Substance ID:DTXSID4045139
Nikkaji Number:J199.807B
Wikipedia:Fenclonine
Wikidata:Q5443204
NCI Thesaurus Code:C81112
ChEMBL ID:CHEMBL1256351
Mol file:7424-00-2.mol

Synonyms:CP-10,188;DL-3-(4-Chlorophenyl)alanine;Fenclonin;Fenclonine;Fenclonine (L)-Isomer;Fenclonine Hydrobromide;Fenclonine Hydrochloride;Fenclonine, (D)-Isomer;Hydrobromide, Fenclonine;Hydrochloride, Fenclonine;p-Chlorophenylalanine;para Chlorophenylalanine;para-Chlorophenylalanine

Suppliers and Price of Fenclonine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
p-Chlorophenylalanine
100mg
$ 296.00

TRC
4-Chloro-DL-phenylalanine
5g
$ 50.00

Tocris
p-Chlorophenylalanine ≥99%(HPLC)
100
$ 63.00

TCI Chemical
4-Chloro-DL-phenylalanine >98.0%(T)
25g
$ 229.00

TCI Chemical
4-Chloro-DL-phenylalanine >98.0%(T)
1g
$ 26.00

Sigma-Aldrich
4-Chloro-DL-phenylalanine
5g
$ 121.00

Sigma-Aldrich
4-Chloro-DL-phenylalanine
25g
$ 452.00

Crysdot
H-DL-Phe(4-Cl)-OH 98+%
100g
$ 218.00

ChemScene
Fenclonine 99.92%
1g
$ 60.00

ChemScene
Fenclonine 99.92%
500mg
$ 50.00

Total 85 raw suppliers

Chemical Property of Fenclonine Edit

Chemical Property:

Appearance/Colour:Crystalline
Melting Point:>240 °C (dec.)(lit.)
Refractive Index:1.5790 (estimate)
Boiling Point:339.5 °C at 760 mmHg
PKA:pK1: 2.08(+1);pK2: 8.96(0) (25°C)
Flash Point:159.1 °C
PSA：63.32000
Density:1.336 g/cm³
LogP:1.99470
Storage Temp.:−20°C
Solubility.:Aqueous Acid (Slightly), Methanol (Slightly)
Water Solubility.:slightly soluble
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:199.0400063
Heavy Atom Count:13
Complexity:179

Purity/Quality:

99.0% ^*data from raw suppliers

p-Chlorophenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25-43
Safety Statements: 36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)N)Cl
Uses An irreversible tryptophan hydroxylase inhibitor. 4-Chloro-DL-phenylalanine is an irreversible tryptophan hydroxylase inhibitor that depletes serotonin in the brain. 4-Chloro-DL-phenylalanine has been used:as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras+ male zebrafishto induce insomnia in rat modelsused to treat embryos to examine its effect on serotoninfor the selection of Enterococcus faecalis transformants with pESentA32 plasmidto feed flies to explore serotonin effect

Technology Process of Fenclonine

There total 21 articles about Fenclonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%