1,3-dihydroxypropan-2-one 1,3-diiopanoate

Base Information

• Chemical Name: 1,3-dihydroxypropan-2-one 1,3-diiopanoate
• CAS No.: 103959-66-6
• Molecular Formula: C₂₅H₂₆I₆N₂O₅
• Molecular Weight: 1195.92
• Mol file: 103959-66-6.mol

Synonyms:1,3-dihydroxypropan-2-one 1,3-diiopanoate

Chemical Property of 1,3-dihydroxypropan-2-one 1,3-diiopanoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1,3-dihydroxypropan-2-one 1,3-diiopanoate

There total 1 articles about 1,3-dihydroxypropan-2-one 1,3-diiopanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1,3-dihydroxyacetone dimer (62147-49-3) + iopanoic acid (96-83-3) → 1,3-dihydroxypropan-2-one 1,3-diiopanoate (103959-66-6)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 66h;

DOI:10.1021/jm00162a007

Reference yield: 75.0%

1,3-dihydroxypropan-2-one 1,3-diiopanoate (103959-66-6) → glyceryl 1,3-diiopanoate (103980-81-0)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; water; benzene; at 5 ℃; for 0.5h;

DOI:10.1021/jm00162a007

Reference yield:

1,3-dihydroxypropan-2-one 1,3-diiopanoate (103959-66-6) → 2-palmitoylglycerol 1,3-diiopanoate (103959-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / NaBH₄ / tetrahydrofuran; benzene; H₂O / 0.5 h / 5 °C

2: 75 percent / 4-dimethylaminopyridine (DMAP), 1,3-dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 66 h

With dmap; sodium tetrahydroborate; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water; benzene;

DOI:10.1021/jm00162a007

upstream raw materials:

1,3-dihydroxyacetone dimer

iopanoic acid

Downstream raw materials:

glyceryl 1,3-diiopanoate

2-palmitoylglycerol 1,3-diiopanoate

glyceryl 1,2,3-triiopanoate

Refernces