Glypallidifloric acid

Base Information

• Chemical Name: Glypallidifloric acid
• CAS No.: 17991-81-0
• Molecular Formula: C₃₀H₄₆O₃
• Molecular Weight: 454.693
• Mol file: 17991-81-0.mol

Synonyms:3β-Hydroxy-Δ11.13(18)-oleanadien-30-saeure;3β-hydroxy-oleanadien-(11.13(18))-oic acid-(30);3β-Hydroxy-oleanadien-(11.13(18))-saeure-(30);(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b-octadecahydro-picene-2-carboxylic acid;

Chemical Property of Glypallidifloric acid

Chemical Property:

• Boiling Point: 565.5±50.0 °C(Predicted)
• PSA: 57.53000
• Density: 1.11±0.1 g/cm3(Predicted)
• LogP: 7.15370

Purity/Quality:

(3β,20β)-3-Hydroxy-oleana-11,13(18)-dien-29-oicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (3β,20β)-3-Hydroxy-oleana-11,13(18)-dien-29-oic acid is a natural steroid found in G. pallidiflora.

Technology Process of Glypallidifloric acid

There total 10 articles about Glypallidifloric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(3β,20β)-3-(acetyloxy)oleana-11,13(18)-dien-29-oic acid methyl ester (230614-29-6) → 3β-Hydroxyolean-11,13(18)-dien-30-oic acid (17991-81-0)

Guidance literature:

With potassium hydroxide; In ethanol; for 6h; Heating;

DOI:10.1080/00304949909355708

Reference yield:

Methyl 3β,11-dihydroxyolean-12-en-30-oate → 3β-Hydroxyolean-11,13(18)-dien-30-oic acid (17991-81-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / HCl; H₂O / 2 h / Heating

2: 98 percent / KOH / ethanol / 6 h / Heating

With hydrogenchloride; potassium hydroxide; water; In ethanol; 1: Acetylation / 2: Deacetylation;

DOI:10.1080/00304949909355708

Reference yield:

(3β,18β,20β)-3-hydroxyoleana-9(11),12-dien-29-oic acid (14884-88-9) → 3β-Hydroxyolean-11,13(18)-dien-30-oic acid (17991-81-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / HCl; H₂O / 4 h / Heating

2: 98 percent / KOH / ethanol / 6 h / Heating

With hydrogenchloride; potassium hydroxide; water; In ethanol; 1: Acetylation / 2: Deacetylation;

DOI:10.1080/00304949909355708

upstream raw materials:

enoxolone

3β-acetoxy-oleanadien-(11.13(18))-oic acid-(30)-methyl ester

(3β,20β)-3-(acetyloxy)oleana-11,13(18)-dien-29-oic acid methyl ester

ethanol

Refernces