4-cyano-5-(cyanoamino)imidazole

Base Information

• Chemical Name: 4-cyano-5-(cyanoamino)imidazole
• CAS No.: 85029-13-6
• Molecular Formula: C₅H₃N₅
• Molecular Weight: 133.112
• Mol file: 85029-13-6.mol

Synonyms:4-cyano-5-(cyanoamino)imidazole

Chemical Property of 4-cyano-5-(cyanoamino)imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-cyano-5-(cyanoamino)imidazole

There total 2 articles about 4-cyano-5-(cyanoamino)imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

2,6 dichloropurine (5451-40-1) → 4-cyano-5-(cyanoamino)imidazole (85029-13-6) + 2-chloroadenine (1839-18-5) + 2,6-diaminopurine (1904-98-9)

Guidance literature:

With potassium amide; In ammonia; at -33 ℃; for 20h;

DOI:10.1021/jo00156a013

Reference yield:

2-Amino-6-chloropurin (10310-21-1) → 4-cyano-5-(cyanoamino)imidazole (85029-13-6) + 2,6-diaminopurine (1904-98-9)

Guidance literature:

With potassium amide; In ammonia; at -33 ℃; for 20h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00156a013

Reference yield:

4-cyano-5-(cyanoamino)imidazole (85029-13-6) → 2,6-diaminopurine (1904-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: KNH₂ / liquid ammonia

2: Heating

With potassium amide; In ammonia;

DOI:10.1021/jo00156a013

upstream raw materials:

2-Amino-6-chloropurin

2,6 dichloropurine

Downstream raw materials:

2,6-diaminopurine

Refernces