m-phenoxy-α-methylbenzyl bromide

Base Information

• Chemical Name: m-phenoxy-α-methylbenzyl bromide
• CAS No.: 32852-94-1
• Molecular Formula: C₁₄H₁₃BrO
• Molecular Weight: 277.161
• Mol file: 32852-94-1.mol

Synonyms:m-phenoxy-α-methylbenzyl bromide

Chemical Property of m-phenoxy-α-methylbenzyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of m-phenoxy-α-methylbenzyl bromide

There total 4 articles about m-phenoxy-α-methylbenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(RS)-1-(3-phenoxyphenyl)ethanol (32852-93-0) → m-phenoxy-α-methylbenzyl bromide (32852-94-1)

Guidance literature:

With phosphorus tribromide; In dichloromethane;

Reference yield:

3'-phenoxyacetophenone (32852-92-9) → m-phenoxy-α-methylbenzyl bromide (32852-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate

2: phosphorus tribromide

With sodium tetrahydroborate; phosphorus tribromide;

Reference yield:

phenol (108-95-2,27073-41-2) → m-phenoxy-α-methylbenzyl bromide (32852-94-1)

Guidance literature:

Multi-step reaction with 3 steps

1: acetylacetone; potassium carbonate; copper(I) bromide / N,N-dimethyl-formamide / 7 h / 120 °C

2: sodium tetrahydroborate; methanol / 20 °C

3: phosphorus tribromide / dichloromethane

With methanol; sodium tetrahydroborate; phosphorus tribromide; potassium carbonate; acetylacetone; copper(I) bromide; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

(RS)-1-(3-phenoxyphenyl)ethanol

3'-phenoxyacetophenone

1-(3-Bromophenyl)ethanone

phenol

Downstream raw materials:

2-(3-Phenoxy-phenyl)-propionic acid

2-(3-Phenoxy-phenyl)-propionic acid

1-Methyl-3-[2-(3-phenoxy-phenyl)-propyl]-urea

2-(3-Phenoxy-phenyl)-propylamine

Refernces