Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipentadecanoin, L-

Base Information

• Chemical Name: Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipentadecanoin, L-
• CAS No.: 3355-27-9
• Molecular Formula: C₃₈H₇₆NO₈P
• Molecular Weight: 705.997
• DSSTox Substance ID: DTXSID60955183
• Mol file: 3355-27-9.mol

Synonyms:diC15-PC;dipentadecanoylphosphatidylcholine

Chemical Property of Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipentadecanoin, L-

Chemical Property:

• PSA: 121.00000
• LogP: 10.90180
• Storage Temp.: −20°C
• XLogP3: 12.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 38
• Exact Mass: 706.53868041
• Heavy Atom Count: 48
• Complexity: 804

Purity/Quality:

99%, ^*data from raw suppliers

1,2-DI-PENTADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCC
• Uses: 1,2-Dipentadecanoyl-sn-glycero-3-phosphocholine is used in liposomal formulation for joint lubrication.

Technology Process of Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipentadecanoin, L-

There total 2 articles about Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipentadecanoin, L- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromoethylphosphoric acid dichloride (4167-02-6) + 1,2-Dipentadecanoyl-rac-glycerol (98896-79-8) + trimethylamine (75-50-3) → dimyristoylphosphatidylcholine (67896-63-3,3355-27-9)

Guidance literature:

Multistep reaction; (i) Et₃N, CHCl₃, (ii) aq. KCl, (iii) /BRN= 956566/;

DOI:10.1002/jlac.19677090124

Reference yield:

pentadecanoyl chloride (17746-08-6) + L-glycero-3-phosphorylcholine (28319-77-9,563-24-6) → 1,2-dipentadecanoyl-sn-glycero-3-phosphorylcholine (3355-27-9)

Guidance literature:

In chloroform;

upstream raw materials:

2-bromoethylphosphoric acid dichloride

1,2-Dipentadecanoyl-rac-glycerol

trimethylamine

pentadecanoyl chloride

Refernces