(+)-6-β-D-Glucopyranosyl-5,7-dihydroxy-2H-1-benzopyran-2-one

Base Information

• Chemical Name: (+)-6-β-D-Glucopyranosyl-5,7-dihydroxy-2H-1-benzopyran-2-one
• CAS No.: 84740-26-1
• Molecular Formula: C15H16O9
• Molecular Weight: 340.28214
• Mol file: 84740-26-1.mol

Synonyms:mulberroside;dauroside D;

Chemical Property of (+)-6-β-D-Glucopyranosyl-5,7-dihydroxy-2H-1-benzopyran-2-one

Chemical Property:

• PSA: 160.82000
• LogP: -1.28090

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (+)-6-β-D-Glucopyranosyl-5,7-dihydroxy-2H-1-benzopyran-2-one

There total 2 articles about (+)-6-β-D-Glucopyranosyl-5,7-dihydroxy-2H-1-benzopyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

5,7-dihydroxy-2H-chromen-2-one (2732-18-5) + D-glucose (50-99-7) → 6-(C-β-D-glucosyl)-5,7-dihydroxycoumarin (84740-26-1)

Guidance literature:

With E_. coli whole cells harboring coumarin C-glucosyltransferase from Morus alba (MaCGT); at 30 ℃; for 24h; Enzymatic reaction;

DOI:10.1002/adsc.202100041

Reference yield: 80.0%

UDP-glucose (133-89-1) + 5,7-dihydroxy-2H-chromen-2-one (2732-18-5) → 6-(C-β-D-glucosyl)-5,7-dihydroxycoumarin (84740-26-1)

Guidance literature:

With C-glycosyltransferase; In aq. phosphate buffer; at 30 ℃; for 12h; pH=8; Enzymatic reaction;

DOI:10.1021/acs.orglett.8b00378

Reference yield:

6-(C-β-D-glucosyl)-5,7-dihydroxycoumarin (84740-26-1) → 5,7-dihydroxy-2H-chromen-2-one (2732-18-5)

Guidance literature:

With Kiliani's mixture; for 6h; Heating;

DOI:10.1007/BF00575694

upstream raw materials:

UDP-glucose

5,7-dihydroxy-2H-chromen-2-one

D-glucose

Downstream raw materials:

5,7-dihydroxy-2H-chromen-2-one

Refernces

• 1、 Chen, Dawei,Fan, Shuai,Yang, Zhaoyong,Dai, Jungui. "Biocatalytic Application of a Membrane-Bound Coumarin C-Glucosyltransferase in the Synthesis of Coumarin and Benzofuran C-Glucosides". . p. 5072 - 5078. Retrieved 2021.