(R)-2-thienylbenzyl alcohol acetate

Base Information

• Chemical Name: (R)-2-thienylbenzyl alcohol acetate
• CAS No.: 118682-57-8
• Molecular Formula: C₁₃H₁₂O₂S
• Molecular Weight: 232.303
• Mol file: 118682-57-8.mol

Synonyms:(R)-2-thienylbenzyl alcohol acetate

Chemical Property of (R)-2-thienylbenzyl alcohol acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-thienylbenzyl alcohol acetate

There total 2 articles about (R)-2-thienylbenzyl alcohol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetic anhydride (108-24-7) + (R)-1-(2-thienyl)-phenyl-methanol (26059-21-2,105748-50-3,118759-49-2) → (R)-2-thienylbenzyl alcohol acetate (118682-57-8)

Guidance literature:

With pyridine;

DOI:10.1021/jo00265a055

Reference yield:

phenyl-thiophen-2-yl-methanol (26059-21-2,105748-50-3,118759-49-2) → (R)-2-thienylbenzyl alcohol acetate (118682-57-8)

Guidance literature:

Multi-step reaction with 2 steps

2: 90 percent / pyridine

With pyridine;

DOI:10.1021/jo00265a055

Reference yield:

(R)-2-thienylbenzyl alcohol acetate (118682-57-8) → (R)-(-)-O-acetylmandelic acid (51019-43-3)

Guidance literature:

With sodium periodate; ruthenium trichloride; In tetrachloromethane; water; acetonitrile; for 1h; Ambient temperature;

DOI:10.1021/jo00265a055

upstream raw materials:

acetic anhydride

(R)-1-(2-thienyl)-phenyl-methanol

phenyl-thiophen-2-yl-methanol

Downstream raw materials:

(R)-(-)-O-acetylmandelic acid

(R)-Mandelic Acid

Refernces