2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl-

Base Information

• Chemical Name: 2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl-
• CAS No.: 15222-64-7
• Molecular Formula: C10H12 O2
• Molecular Weight: 164.204
• Hs Code.: 2916209090
• European Community (EC) Number: 239-273-8
• Nikkaji Number: J276C
• Mol file: 15222-64-7.mol

Synonyms:15222-64-7;2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl-;2-Propenoic acid,3-bicyclo[2.2.1]hept-5-en-2-yl-;3-{bicyclo[2.2.1]hept-5-en-2-yl}prop-2-enoic acid;Norborn-5-en-2-acrylic acid;SCHEMBL600200;PSQVRPSVCYLDTE-ONEGZZNKSA-N;5-NORBORNENE-2-ACRYLICACID;EN300-1841072;(2E)-3-Bicyclo[2.2.1]hept-5-en-2-yl-2-propenoic acid;(E)-3-(2-bicyclo[2.2.1]hept-5-enyl)prop-2-enoic acid;(2E)-3-Bicyclo[2.2.1]hept-5-en-2-yl-2-propenoic acid #

Chemical Property of 2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl-

Chemical Property:

• Vapor Pressure: 0.000109mmHg at 25°C
• Refractive Index: 1.5460 (estimate)
• Boiling Point: 313.3°Cat760mmHg
• Flash Point: 218.1°C
• PSA: 37.30000
• Density: 1.272g/cm³
• LogP: 1.83940
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 253

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-NORBORNENE-2-ACRYLIC ACID AldrichCPR ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2CC(C1C=C2)C=CC(=O)O
• Isomeric SMILES: C1C2CC(C1C=C2)/C=C/C(=O)O

Technology Process of 2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl-

There total 3 articles about 2-Propenoic acid, 3-bicyclo[2.2.1]hept-5-en-2-yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Norbornene-2-carboxaldehyde (5453-80-5,19926-90-0) + malonic acid (141-82-2) → β-hepten-(5)-yl-(2)>-acrylsaeure (15222-64-7)

Guidance literature:

With piperidine; In benzene; Heating;

Reference yield:

5-Norbornene-2-carboxaldehyde (5453-80-5,19926-90-0) + diethyl <<(trimethylsilyl)oxy>carbonyl>methanephosphonate (66130-90-3) → 3-(5-norbornen-2-yl)acrylic acid (15222-64-7,102977-30-0)

Guidance literature:

With n-butyllithium; Multistep reaction; 1.) THF, hexane, overnight, 2.) RT, overnight;

DOI:10.1021/jo00365a032

Reference yield:

malonic acid (141-82-2) + (+/-)-endo-bicyclo[2.2.1]hept-5-ene-2-carbaldehyde (19926-90-0) → (+/-)-3t-norborn-5-ene-2endo-yl-acrylic acid (15222-64-7,102977-30-0)

Guidance literature:

With piperidine; pyridine;

DOI:10.1021/ja01165a072

upstream raw materials:

5-Norbornene-2-carboxaldehyde

malonic acid

(+/-)-endo-bicyclo[2.2.1]hept-5-ene-2-carbaldehyde

diethyl <<(trimethylsilyl)oxy>carbonyl>methanephosphonate

Downstream raw materials:

2-((E)-3-Bicyclo[2.2.1]hept-5-en-2-yl-acryloylamino)-3-phenyl-propionic acid

Refernces