2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine

Base Information

• Chemical Name: 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine
• CAS No.: 1245317-48-9
• Molecular Formula: C₁₁H₁₆N₄O₃
• Molecular Weight: 252.273
• Mol file: 1245317-48-9.mol

Synonyms:2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine

Chemical Property of 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine

There total 2 articles about 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine (1245317-48-9)

Guidance literature:

With sodium hydroxide; at 20 ℃; for 1h; Cooling with ice;

With hydrogenchloride; pH=5;

Reference yield: 87.0%

2,5-diamino-4,6-dihydroxypyrimidine hydrochloride (40769-69-5) + cyclohexanylcarbonyl chloride (2719-27-9) → 2-amino-5-cyclohexanecarboxamido-4,6-dihydroxypyrimidine (1245317-48-9)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 1h; Cooling with ice;

upstream raw materials:

2,5-diamino-4,6-dihydroxypyrimidine hydrochloride

cyclohexanylcarbonyl chloride

Refernces

• 1、 -. "Antiviral Activity of Novel Bicyclic Heterocycles". Paragraph 0737; 0738; 0739; 0740. . Retrieved 2013/07/31.