Technology Process of (3R,4R)-methyl 4-(hydroxy(phenyl)amino)-3-(naphthalen-2-yl)-4-phenylbutanoate
There total 1 articles about (3R,4R)-methyl 4-(hydroxy(phenyl)amino)-3-(naphthalen-2-yl)-4-phenylbutanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-3-(2-naphthyl)-2-propenal; C,N-diphenylnitrone;
With
triethylamine;
chiral triazolium salt;
In
dichloromethane;
at -25 ℃;
for 48h;
sodium methylate;
In
methanol;
at 0 ℃;
for 0.0166667h;
Further stages. Title compound not separated from byproducts.;
DOI:10.1021/ja710521m
