2,3,5,6-Tetrachloropyridine-4-thiol

Base Information

• Chemical Name: 2,3,5,6-Tetrachloropyridine-4-thiol
• CAS No.: 10351-06-1
• Molecular Formula: C5HCl4NS
• Molecular Weight: 248.948
• Hs Code.: 2933399090
• European Community (EC) Number: 233-764-0
• UNII: JJDWPEXDAY
• DSSTox Substance ID: DTXSID60145885
• Nikkaji Number: J236.784J
• Mol file: 10351-06-1.mol

Synonyms:2,3,5,6-Tetrachloropyridine-4-thiol;10351-06-1;2,3,5,6-Tetrachloro-4-mercaptopyridine;2,3,5,6-tetrachloro-1H-pyridine-4-thione;Tetrachloropyridine-4-thiol;JJDWPEXDAY;EINECS 233-764-0;4-Pyridinethiol, 2,3,5,6-tetrachloro-;C5HCl4NS;2,3,5,6-Tetrachloro-4-pyridinethiol;UNII-JJDWPEXDAY;C5-H-Cl4-N-S;SCHEMBL612835;DTXSID60145885;LVUQDNJRAHUUSB-UHFFFAOYSA-N;Isothiocyanicacid4-penten-1-ylester;MFCD00006231;AKOS015891918;2,3,5,6- Tetrachloropyridine-4-thiol;AS-62303;CS-0060007;FT-0609404;W17245;A800756;2,3,5,6-tetrakis(chloranyl)-1H-pyridine-4-thione;W-108847

Chemical Property of 2,3,5,6-Tetrachloropyridine-4-thiol

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0.262mmHg at 25°C
• Melting Point: 165-166 °C(lit.)
• Refractive Index: 1.677
• Boiling Point: 204.6 °C at 760 mmHg
• PKA: 2.01±0.50(Predicted)
• Flash Point: 77.5 °C
• PSA: 51.69000
• Density: 1.79 g/cm³
• LogP: 3.98390
• Storage Temp.: 2-8°C
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 248.855431
• Heavy Atom Count: 11
• Complexity: 254

Purity/Quality:

98% ^*data from raw suppliers

2,3,5,6-Tetrachloropyridine-4-thiol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(NC(=C(C1=S)Cl)Cl)Cl)Cl

Technology Process of 2,3,5,6-Tetrachloropyridine-4-thiol

There total 2 articles about 2,3,5,6-Tetrachloropyridine-4-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.4%

4-trifluoromethylthio-2,3,5,6-tetrachloropyridine (129626-65-9) → 2,3,5,6-tetrachloro-4-mercaptopyridine (10351-06-1)

Guidance literature:

With sodium hydrogensulfide; In methanol; for 0.25h; Ambient temperature;

DOI:10.1007/BF01164733

Reference yield:

→ 2,3,5,6-tetrachloro-4-mercaptopyridine (10351-06-1)

Guidance literature:

Pentachlorpyridin;

DOI:10.1039/j39700000193

Reference yield: 82.0%

2,3,5,6-tetrachloro-4-mercaptopyridine (10351-06-1) + 4-Chlormethyl-3-(3-trifluormethylphenyl)-2,3-dihydro-1,3-thiazol-2-thion (286374-52-5) → 4-(2,3,5,6-Tetrachlorpyridin-4-ylsulfanylmethyl)-3-(3-trifluormethylphenyl)-2,3-dihydro-1,3-thiazol-2-thion

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In methanol; at 20 ℃; for 24h;

upstream raw materials:

4-trifluoromethylthio-2,3,5,6-tetrachloropyridine

Refernces

• 1、 Moshchitskii et al.. "-". . . Retrieved 1977.