C₁₄H₁₃ClO₂

Base Information

• Chemical Name: C₁₄H₁₃ClO₂
• CAS No.: 651323-26-1
• Molecular Formula: C₁₄H₁₃ClO₂
• Molecular Weight: 248.709
• Mol file: 651323-26-1.mol

Synonyms:C₁₄H₁₃ClO₂

Chemical Property of C₁₄H₁₃ClO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₃ClO₂

There total 3 articles about C₁₄H₁₃ClO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chlorobenzil (22711-23-5) → (1R,2R)-1-(4'-chlorophenyl)-2-phenylethane-1,2-diol (62086-76-4) + C14H13ClO2 (651323-26-1)

Guidance literature:

With formic acid; triethylamine; In acetonitrile; at 50 ℃; for 40h; Overall yield = 97.4 %; enantioselective reaction;

DOI:10.1016/j.apcata.2014.03.039

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + LDH-PdOsW + 1-Chloro-4-iodobenzene (637-87-6) → 1-(4-chloro-phenyl)-2-phenyl-ethane-1,2-diol (651323-26-1)

Guidance literature:

With NMM; dihydrogen peroxide; triethylamine; In tbutanol-water; hexane; ethyl acetate;

Reference yield:

4-chlorobenzil (22711-23-5) → 1-(4-chloro-phenyl)-2-phenyl-ethane-1,2-diol (651323-26-1) + (1S,2S)-1-(4'-chlorophenyl)-2-phenylethane-1,2-diol

Guidance literature:

With Ru(OTf)(TsDPEN)(η6-cymene); hydrogen; In methanol; at 20 ℃; for 24h; under 22801.5 Torr; Overall yield = 72 %; enantioselective reaction; Autoclave; Inert atmosphere;

DOI:10.1002/cjoc.201200393

upstream raw materials:

styrene

1-Chloro-4-iodobenzene

4-chlorobenzil

Downstream raw materials:

4-chlorobenzaldehyde

benzaldehyde

Refernces

• 1、 Huang, Xiaofei,Li, Naikai,Geng, Zhicong,Pan, Fengfeng,Wang, Xingwang. "Stereoselective synthesis of optically active hydrobenzoins via asymmetric hydrogenation of benzils with Ru(OTf)(TsDPEN)(I·6- cymene) as the pre-catalyst". . p. 2657 - 2663. Retrieved 2013/01/15.
• 2、 -. "Multifunctional catalyst useful in the synthesis of chiral vicinal diols and process for the preparation thereof". . . Retrieved 2008/06/13.