allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate

Base Information

• Chemical Name: allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate
• CAS No.: 719297-59-3
• Molecular Formula: C₂₆H₁₈Cl₂O₅
• Molecular Weight: 481.332
• Mol file: 719297-59-3.mol

Synonyms:allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate

Chemical Property of allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate

There total 3 articles about allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,7-dichlorofluorescein (18362-80-6) + allyl bromide (106-95-6) → allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate (719297-59-3)

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 3h;

Reference yield: 10.0%

2',7'-dichlorofluorescein (76-54-0) + allyl bromide (106-95-6) → C26H18Cl2O5 + allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate (719297-59-3)

Guidance literature:

2',7'-dichlorofluorescein; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

allyl bromide; In N,N-dimethyl-formamide; at 70 ℃;

DOI:10.1021/acs.analchem.7b00135

Reference yield:

2',7'-dichlorofluorescein (76-54-0) + allyl bromide (106-95-6) → allyl 2-(6-(allyloxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl)benzoate (719297-59-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2.5h;

DOI:10.1039/c4tb01563k

upstream raw materials:

2,7-dichlorofluorescein

allyl bromide

2',7'-dichlorofluorescein

Downstream raw materials:

Pittsburgh Yellow

C₃₃H₂₁Cl₂F₃O₆

C₃₂H₂₂Cl₂O₇

C₃₃H₂₄Cl₂O₇

Refernces

• 1、 Sparano, Brian A.,Shahi, Shatrughan P.,Koide, Kazunori. "Effect of binding and conformation on fluorescence quenching in new 2′,7′-dichlorofluorescein derivatives". . p. 1947 - 1949. Retrieved 2004.
• 2、 -. "A phenyl [...] hERG potassium ion channel of small molecule fluorescent probe and its application (by machine translation)". Paragraph 0047; 0048. . Retrieved 2016/11/24.