Technology Process of (2S,3R,4R,5S)-3-Benzyloxy-5-benzyloxymethoxy-7-(4-methoxy-benzyloxy)-2,4-dimethyl-heptanal
There total 10 articles about (2S,3R,4R,5S)-3-Benzyloxy-5-benzyloxymethoxy-7-(4-methoxy-benzyloxy)-2,4-dimethyl-heptanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfur trioxide pyridine complex; triethylamine;
In
dichloromethane; dimethyl sulfoxide;
at 20 ℃;
for 3h;
DOI:10.1021/ja0279646
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 93 percent / NaHMDS / tetrahydrofuran; dimethylformamide / 1 h / 20 °C
2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 8 h / 20 °C
3: 96 percent / triethylamine; sulfur trioxide pyridine complex / dimethylsulfoxide; CH2Cl2 / 3 h / 20 °C
With
tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; sulfur trioxide pyridine complex; triethylamine;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ja0279646
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / imidazole / CH2Cl2 / 1 h / 0 °C
2: 93 percent / NaHMDS / tetrahydrofuran; dimethylformamide / 1 h / 20 °C
3: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 8 h / 20 °C
4: 96 percent / triethylamine; sulfur trioxide pyridine complex / dimethylsulfoxide; CH2Cl2 / 3 h / 20 °C
With
1H-imidazole; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; sulfur trioxide pyridine complex; triethylamine;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ja0279646
