C₁₃H₁₁N₃O₂S

Base Information

• Chemical Name: C₁₃H₁₁N₃O₂S
• CAS No.: 1281979-66-5
• Molecular Formula: C₁₃H₁₁N₃O₂S
• Molecular Weight: 273.315
• Mol file: 1281979-66-5.mol

Synonyms:C₁₃H₁₁N₃O₂S

Chemical Property of C₁₃H₁₁N₃O₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₁N₃O₂S

There total 4 articles about C₁₃H₁₁N₃O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-(3-nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one (13982-55-3,135950-58-2) → C13H11N3O2S (1281979-66-5)

Guidance literature:

With hydrazine hydrochloride; In N,N-dimethyl-formamide; for 2h; Reflux;

Reference yield:

C13H9NO3S (40665-03-0) → C13H11N3O2S (1281979-66-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 5h; Reflux;

DOI:10.1016/j.bioorg.2021.105134

Reference yield:

3-Nitroacetophenone (121-89-1) → C13H11N3O2S (1281979-66-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 24 h / 0 - 20 °C

2: hydrazine hydrate / ethanol / 5 h / Reflux

With hydrazine hydrate; sodium hydroxide; In ethanol; water;

DOI:10.1016/j.bioorg.2021.105134

upstream raw materials:

3-(3-nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one

C₁₃H₉NO₃S

3-Nitroacetophenone

thiophene-2-carbaldehyde

Refernces

• 1、 Ingle,Doshi,Raut. "Synthesis and structural studies of isomeric Δ2- pyrazolines". experimental part. p. 1517 - 1520. Retrieved 2011/10/13.