MES sodium

Base Information

• Chemical Name: MES sodium
• CAS No.: 71119-23-8
• Molecular Formula: C6H12NNaO4S
• Molecular Weight: 217.221
• Hs Code.: 29349990
• Mol file: 71119-23-8.mol

Synonyms:2-(4-Morpholino)ethanesulfonic acid hemisodium salt;MES sodium;SCHEMBL285411;SADPCIINLASURY-UHFFFAOYSA-N;AKOS040758303

Chemical Property of MES sodium

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0Pa at 25℃
• PSA: 78.05000
• Density: 1.507[at 20℃]
• LogP: -0.11750
• Storage Temp.: Store at RT.
• Solubility.: H2O: 0.5 g/mL, clear, colorless
• Water Solubility.: H2O: 0.5 g/mL, clear, colorless
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 218.04629835
• Heavy Atom Count: 13
• Complexity: 214

Purity/Quality:

99% ^*data from raw suppliers

MES, Sodium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CCS(=O)(=O)O.[Na]
• Uses: MES sodium salt is a buffering agent used in biological and biochemical research including plant cell culture. MES sodium salt has been used:To achieve the required density and stretching of DNA fibers during melting of agarose plugs containing genomic DNATo equilibrate the Balch homogenizer chamber and to prevent sample hydrolysis before sample homogenization MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Technology Process of MES sodium

There total 1 articles about MES sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.2%

morpholine (110-91-8,99108-56-2) + sodium 2-hydroxyethanesulfonate (1562-00-1) → 2-(N-morpholino)ethanesulfonic acid sodium salt (71119-23-8)

Guidance literature:

sodium hydroxide; In water; at 200 ℃; for 2 - 4h; under 3345.86 - 8517.48 Torr; Product distribution / selectivity; Autoclave;

upstream raw materials:

morpholine

sodium 2-hydroxyethanesulfonate

Refernces