2-ethyl-4-fluoro-phenetole

Base Information

• Chemical Name: 2-ethyl-4-fluoro-phenetole
• CAS No.: 324-44-7
• Molecular Formula: C₁₀H₁₃FO
• Molecular Weight: 168.211
• Mol file: 324-44-7.mol

Synonyms:2-ethyl-4-fluoro-phenetole

Chemical Property of 2-ethyl-4-fluoro-phenetole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethyl-4-fluoro-phenetole

There total 2 articles about 2-ethyl-4-fluoro-phenetole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-ethoxy-5-fluorophenyl)-1-ethanol (577-97-9) → 2-ethyl-4-fluoro-phenetole (324-44-7) + 2,3-bis-(2-ethoxy-5-fluoro-phenyl)-butane

Guidance literature:

With hydrogenchloride; toluene; at 0 ℃; Umsetzung des gebildeten Chlorids mit Magnesium in Aether und anschliessende Hydrolyse mit wss. Saeure bei 0grad;

DOI:10.1021/ja01870a052

Reference yield:

1-(2-ethoxy-5-fluorophenyl)-1-ethanol (577-97-9) → 2-ethyl-4-fluoro-phenetole (324-44-7)

Guidance literature:

With phosphoric acid; at 200 ℃; under 10 Torr; Hydrierung des Reaktionsprodukts an Platin in Aethanol unter Druck;

Reference yield:

2-ethyl-4-fluoro-phenetole (324-44-7) → 2-ethyl-4-fluorophenol (398-71-0)

Guidance literature:

With hydrogen iodide; acetic acid;

DOI:10.1021/ja01870a052

upstream raw materials:

1-(2-ethoxy-5-fluorophenyl)-1-ethanol

Downstream raw materials:

2-ethyl-4-fluorophenol

2-(2-ethyl-4-fluorophenoxy)acetic acid