Gedunin deacetyl-

Base Information Edit

Chemical Name:Gedunin deacetyl-
CAS No.:10314-90-6
Molecular Formula:C₂₆H₃₂O₆
Molecular Weight:440.536
Hs Code.:
NSC Number:309912
DSSTox Substance ID:DTXSID80908212
Wikidata:Q105025652
ChEMBL ID:CHEMBL1981983
Mol file:10314-90-6.mol

Synonyms:7-Deacetoxy-7-hydroxygedunin;GEDUNIN DEACETYL-;NSC309912;16,17-Seco-24-nor-5.alpha.,13.alpha.,14.beta.,17.alpha.-chola-1,20,22-trien-16-oic acid, 14,15.beta.:21,23-diepoxy-7.alpha.,17-dihydroxy-4,4,8-trimethyl-3-oxo-, 16,17-lactone;D-Homo-24-nor-17-oxachola-1,20,22-triene-3,16-dione, 14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-, (5.alpha.,7.alpha.,13.alpha.,14.beta.,15.beta.,17a.alpha.)-;C26H32O6;C26-H32-O6;CHEMBL1981983;DTXSID80908212;HCEYJYMNIQHPPK-UHFFFAOYSA-N;NSC-309912;NCI60_002663;1-(3-Furyl)-5-hydroxy-4b,7,7,10a,12a-pentamethyl-1,5,6,6a,7,10a,10b,11,12,12a-decahydronaphtho[2,1-f]oxireno[2,3-d]isochromene-3,8(3ah,4bh)-dione #;10-(Furan-3-yl)-6-hydroxy-4,4,6a,10a,12b-pentamethyl-4a,5,6,6a,10,10a,11,12,12a,12b-decahydrooxireno[c]phenanthro[1,2-d]pyran-3,8(4H,7aH)-dione;16,13.alpha.,14.beta.,17.alpha.-chola-1,20,22-trien-16-oic acid, 14,15.beta.:21,23-diepoxy-7.alpha.,17-dihydroxy-4,4,8-trimethyl-3-oxo-, 16,17-lactone;D-Homo-24-nor-17-oxachola-1,22-triene-3,16-dione, 14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-, (5.alpha.,7.alpha.,13.alpha.,14.beta.,15.beta.,17a.alpha.)-

Suppliers and Price of Gedunin deacetyl-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Deacetilgedunin
5mg
$ 765.00

Total 5 raw suppliers

Chemical Property of Gedunin deacetyl- Edit

Chemical Property:

Vapor Pressure:4.75E-15mmHg at 25°C
Boiling Point:596°C at 760 mmHg
Flash Point:314.2°C
PSA：89.27000
Density:1.29g/cm³
LogP:3.98990
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:440.21988874
Heavy Atom Count:32
Complexity:925

Purity/Quality:

98%,99%, ^*data from raw suppliers

7-Deacetilgedunin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2CC(C3(C(C2(C=CC1=O)C)CCC4(C35C(O5)C(=O)OC4C6=COC=C6)C)C)O)C
Uses 7-Deacetilgedunin is a dervative of Gedunin (G303503), a naturally occurring Hsp90 inhibitor. In vitro, Gedunin induces Hsp90-dependent client protein degradation and displays antiproliferative activity. Also an extract from neem seeds and may be responsible for its antibacterial activity.

Technology Process of Gedunin deacetyl-

There total 4 articles about Gedunin deacetyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%