3-Amino-4-hydroxyphenylarsonic acid

Base Information

• Chemical Name: 3-Amino-4-hydroxyphenylarsonic acid
• CAS No.: 2163-77-1
• Molecular Formula: C6H8 As N O4
• Molecular Weight: 233.055
• European Community (EC) Number: 218-494-3
• NSC Number: 18814
• UNII: 6BW7B92RB8
• DSSTox Substance ID: DTXSID20176019
• Nikkaji Number: J33.866D
• Wikidata: Q83046353
• ChEMBL ID: CHEMBL1970917
• Mol file: 2163-77-1.mol

Synonyms:4-hydroxy-3-aminophenylarsonic acid;HAPA cpd

Chemical Property of 3-Amino-4-hydroxyphenylarsonic acid

Chemical Property:

• Vapor Pressure: 1.41E-14mmHg at 25°C
• Melting Point: 290°C (rough estimate)
• Boiling Point: 586°Cat760mmHg
• PKA: 8.53±0.22(Predicted)
• Flash Point: 308.2°C
• PSA: 103.78000
• Density: g/cm³
• LogP: -0.88340
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 232.966927
• Heavy Atom Count: 12
• Complexity: 204

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-1-HYDROXYBENZENE-4-ARSONIC ACID 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1[As](=O)(O)O)N)O

Technology Process of 3-Amino-4-hydroxyphenylarsonic acid

There total 10 articles about 3-Amino-4-hydroxyphenylarsonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

roxarsone (121-19-7) → 3-amino-4-hydroxyphenylarsonic acid (2163-77-1)

Guidance literature:

With hydrogenchloride; bei der elektrolytischen Reduktion an Platin-, Kupfer- oder Nickelkathoden;

Reference yield:

→ 3-amino-4-hydroxyphenylarsonic acid (2163-77-1)

Guidance literature:

With dihydrogen peroxide;

Reference yield:

roxarsone (121-19-7) → 3-amino-4-hydroxyphenylarsonic acid (2163-77-1) + (4,4'-dihydroxy-3,3'-azoxy-diphenyl)-bis-arsonic acid

Guidance literature:

With hydrogenchloride; copper; bei der elektrolytischen Reduktion;

upstream raw materials:

roxarsone

hydrogenchloride

methanol

4-hydroxyphenylarsonic acid

Downstream raw materials:

[3-(4,6-diamino-[1,3,5]triazin-2-ylamino)-4-hydroxy-phenyl]-arsonic acid

(3-ethoxycarbonylamino-4-hydroxy-phenyl)-arsonic acid

[3-(2-chloro-ethoxycarbonylamino)-4-hydroxy-phenyl]-arsonic acid

Refernces