1,2,7,8-Diepoxyoctane

Base Information

• Chemical Name: 1,2,7,8-Diepoxyoctane
• CAS No.: 2426-07-5
• Molecular Formula: C8H14 O2
• Molecular Weight: 142.198
• Hs Code.: 29109000
• European Community (EC) Number: 219-375-9
• NSC Number: 269058
• UNII: 4IJ1M5W7LL
• DSSTox Substance ID: DTXSID00862928
• Nikkaji Number: J2.154G
• Wikidata: Q27109807
• Metabolomics Workbench ID: 53914
• Mol file: 2426-07-5.mol

Synonyms:1,2,7,8-diepoxyoctane

Chemical Property of 1,2,7,8-Diepoxyoctane

Chemical Property:

• Appearance/Colour: clear colorless to slightly yellow liquid
• Vapor Pressure: 0.0602mmHg at 25°C
• Refractive Index: n20/D 1.445(lit.)
• Boiling Point: 240°Cat760mmHg
• Flash Point: 97.8°C
• PSA: 25.06000
• Density: 1.051g/cm³
• LogP: 1.34440
• Storage Temp.: Store below +30°C.
• Solubility.: 7g/l
• Water Solubility.: Soluble in water (partly miscible), acetone and heptane.
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 142.099379685
• Heavy Atom Count: 10
• Complexity: 99.8

Purity/Quality:

98% ^*data from raw suppliers

1,2,7,8-Diepoxyoctane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 22-24-68-45
• Safety Statements: 36/37/39-45-53

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(O1)CCCCC2CO2
• Uses: suzuki reaction 1,2,7,8-Diepoxyoctane is used as an organic chemical synthesis intermediate.

Technology Process of 1,2,7,8-Diepoxyoctane

There total 5 articles about 1,2,7,8-Diepoxyoctane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.2%

1,7-Octadiene (3710-30-3) → 1,2,7,8-diepoxyoctane (2426-07-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃;

DOI:10.1016/j.carres.2011.09.018

Reference yield:

1,7-Octadiene (3710-30-3) → 1,2,7,8-diepoxyoctane (2426-07-5) + 1,2-epoxy-7-octene (52485-73-1,105205-70-7,126872-17-1,19600-63-6)

Guidance literature:

With oxygen; isobutyraldehyde; silica-supported cobalt acetate; In dichloromethane; at 19 ℃; for 24h;

DOI:10.1039/cc9960001859

Reference yield:

1,2-epoxy-7-octene (52485-73-1,105205-70-7,126872-17-1,19600-63-6) → 1,2,7,8-diepoxyoctane (2426-07-5)

Guidance literature:

With potassium peroxomonosulfate; dihydroisoquinolinium tetrafluoroborate; sodium hydrogencarbonate; In water; acetonitrile; at 20 ℃; for 6h;

DOI:10.1016/j.tetlet.2003.11.040

upstream raw materials:

1,7-Octadiene

3,3'-dichloro-1,1'-oxy-bis-propan-2-ol

1,2-epoxy-7-octene

1,7-Octadiyne

Downstream raw materials:

1,8-Octanediol

octane-2,7-diol

benzyl ((S)-2-hydroxy-6-((R)-oxiran-2-yl)hexyl)carbamate

benzyl ((S)-2-hydroxy-6-((S)-oxiran-2-yl)hexyl)carbamate

Refernces

• 1、 -. "One-pot method for preparing diepoxide (by machine translation)". Paragraph 0085-0092. . Retrieved 2020/05/01.
• 2、 -. "METHOD FOR PRODUCING EPOXY COMPOUND BY OXIDATION". Paragraph 0040. . Retrieved 2013/06/27.