2,2'-[Methylenebis(oxy)]bisethanol

Base Information

• Chemical Name: 2,2'-[Methylenebis(oxy)]bisethanol
• CAS No.: 2565-36-8
• Molecular Formula: C5H12 O4
• Molecular Weight: 136.148
• European Community (EC) Number: 219-891-4
• UNII: 2R5HK625EQ
• DSSTox Substance ID: DTXSID90180345
• Nikkaji Number: J192.068E
• Wikidata: Q83050881
• Mol file: 2565-36-8.mol

Synonyms:2565-36-8;2,2'-[METHYLENEBIS(OXY)]BISETHANOL;2,2'-(Methylenebis(oxy))bisethanol;Ethanol, 2,2'-[methylenebis(oxy)]bis-;AI3-03309;EINECS 219-891-4;Ethanol, 2,2'-(methylenebis(oxy))bis-;2,2'-[Methylenebis(oxy)]bis(ethanol);2,2'-[Methylenebis(oxy)]bis[ethanol];2-(2-hydroxyethoxymethoxy)ethanol;Bis(2-hydroxyethoxy)methane;SCHEMBL560852;2R5HK625EQ;DTXSID90180345;Ethanol, 2,2'-(methylenedioxy)di-

Chemical Property of 2,2'-[Methylenebis(oxy)]bisethanol

Chemical Property:

• Boiling Point: 254.5°Cat760mmHg
• Flash Point: 107.7°C
• PSA: 58.92000
• Density: 1.145g/cm³
• LogP: -1.03830
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 136.07355886
• Heavy Atom Count: 9
• Complexity: 42.2

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COCOCCO)O

Technology Process of 2,2'-[Methylenebis(oxy)]bisethanol

There total 6 articles about 2,2'-[Methylenebis(oxy)]bisethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + ethylene glycol (107-21-1) → 1,3-DIOXOLANE (646-06-0) + 2,2'-methanediyldioxy-bis-ethanol (2565-36-8) + ethylene glycol monoformate (628-35-3)

Guidance literature:

With aluminium(III) triflate; [Ru(1,1,1-tris(diphenylphosphinomethyl)ethane)(trimethylenemethane)]; hydrogen; In 1,4-dioxane; at 80 ℃; for 18h; under 60006 Torr; Solvent; Catalytic behavior; Autoclave; Schlenk technique;

DOI:10.1002/chem.201901660

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethylene glycol (107-21-1) → 2,2'-methanediyldioxy-bis-ethanol (2565-36-8)

Guidance literature:

DOI:10.1021/ja00788a017

Reference yield:

1,3-DIOXOLANE (646-06-0) + ethylene glycol (107-21-1) → 2,2'-methanediyldioxy-bis-ethanol (2565-36-8)

Guidance literature:

With sulfuric acid;

DOI:10.1007/BF01134734

upstream raw materials:

1,3-DIOXOLANE

ethylene glycol

formaldehyd

bis-(2-acetoxy-ethoxy)-methane

Downstream raw materials:

2-(methoxymethoxy)ethanol

Refernces

• 1、 Beydoun, Kassem,Klankermayer, Jürgen. "Ruthenium-Catalyzed Synthesis of Cyclic and Linear Acetals by the Combined Utilization of CO2, H2, and Biomass Derived Diols". supporting information. p. 11412 - 11415. Retrieved 2019/07/18.